P 2021

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

PARUCH, Kamil, Benoit Jean-Pierre CARBAIN, Štěpán HAVEL, Jiří DAMBORSKÝ, Jan BREZOVSKÝ et. al.

Basic information

Original name

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

Authors

PARUCH, Kamil (203 Czech Republic, belonging to the institution), Benoit Jean-Pierre CARBAIN (250 France, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Jiří DAMBORSKÝ (203 Czech Republic, belonging to the institution), Jan BREZOVSKÝ (203 Czech Republic, belonging to the institution), Lukáš DANIEL (203 Czech Republic, belonging to the institution), Alexandra SISÁKOVÁ (703 Slovakia, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution) and Lumír KREJČÍ (203 Czech Republic, belonging to the institution)

Edition

Number: EP3556755B1, Publisher: European Patent Office, Place of publication: Mnichov, Owner's name: Masarykova Univerzita, 2021

Other information

Language

English

Type of outcome

Patent

Field of Study

10401 Organic chemistry

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14310/21:00124423

Organization unit

Faculty of Science

Keywords in English

Antineoplastic agents; not condensed and containing further heterocyclic rings; condensed with carbocyclic rings; directly linked by a ring-member-to-ring-member bond; linked by a chain containing hetero atoms as chain links
Změněno: 23/3/2022 09:59, Mgr. Marie Šípková, DiS.

Abstract

V originále

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.