| SUBADINI, Suchismita, Ram Sankar PANIGRAHY, Nishesh Kumar GUPTA, Krishnendu BERA and Harekrushna SAHOO. Impact of Chromate and Dichromate on Lysozyme Stability: A Spectroscopic and Molecular Docking Investigation. Luminescence. Wiley, 2022, vol. 37, No 6, p. 876-882. ISSN 1522-7235. Available from: https://dx.doi.org/10.1002/bio.4231. |
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@article{1842397,
author = {Subadini, Suchismita and Panigrahy, Ram Sankar and Gupta, Nishesh Kumar and Bera, Krishnendu and Sahoo, Harekrushna},
article_number = {6},
doi = {http://dx.doi.org/10.1002/bio.4231},
keywords = {Lyz; fluorescence quenching; anisotropy; chromate; dichromate},
language = {eng},
issn = {1522-7235},
journal = {Luminescence},
title = {Impact of Chromate and Dichromate on Lysozyme Stability: A Spectroscopic and Molecular Docking Investigation},
url = {https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/bio.4231},
volume = {37},
year = {2022}
}
TY - JOUR
ID - 1842397
AU - Subadini, Suchismita - Panigrahy, Ram Sankar - Gupta, Nishesh Kumar - Bera, Krishnendu - Sahoo, Harekrushna
PY - 2022
TI - Impact of Chromate and Dichromate on Lysozyme Stability: A Spectroscopic and Molecular Docking Investigation
JF - Luminescence
VL - 37
IS - 6
SP - 876-882
EP - 876-882
PB - Wiley
SN - 15227235
KW - Lyz
KW - fluorescence quenching
KW - anisotropy
KW - chromate
KW - dichromate
UR - https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/bio.4231
N2 - A comparative study of interaction between Lysozyme (Lyz) with two hexavalent chromate ions; chromate and dichromate; which are prevalently known for their toxicity, was investigated using different spectroscopic techniques along with molecular docking study. Both steady-state and time-resolved studies revealed that the addition of chromate/dichromate is responsible for strong quenching of intrinsic fluorescence in Lyz and the quenching is caused by both static and dynamic quenching mechanism. Different binding and thermodynamic parameters were also calculated at different temperatures from the intrinsic fluorescence of Lyz. The conformational change in Lyz and thermodynamic parameters obtained during the course of interaction with chromate/dichromate were well-supported by the molecular docking results.
ER -
SUBADINI, Suchismita, Ram Sankar PANIGRAHY, Nishesh Kumar GUPTA, Krishnendu BERA and Harekrushna SAHOO. Impact of Chromate and Dichromate on Lysozyme Stability: A Spectroscopic and Molecular Docking Investigation. \textit{Luminescence}. Wiley, 2022, vol.~37, No~6, p.~876-882. ISSN~1522-7235. Available from: https://dx.doi.org/10.1002/bio.4231.
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