DVOŘÁK, Petr, Pavel KREJČÍ, Lukáš BÁLEK, Lívia EISELLEOVÁ, Žaneta KONEČNÁ, Pavel DVOŘÁK, David BEDNÁŘ, Jan BREZOVSKÝ, Eva ŠEBESTOVÁ, Radka CHALOUPKOVÁ, Veronika ŠTĚPÁNKOVÁ, Pavel VAŇÁČEK, Zbyněk PROKOP, Jiří DAMBORSKÝ and Michaela BOSÁKOVÁ. Thermostable FGF2 polypeptide, use thereof. 2021. |
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@misc{1845598, author = {Dvořák, Petr and Krejčí, Pavel and Bálek, Lukáš and Eiselleová, Lívia and Konečná, Žaneta and Dvořák, Pavel and Bednář, David and Brezovský, Jan and Šebestová, Eva and Chaloupková, Radka and Štěpánková, Veronika and Vaňáček, Pavel and Prokop, Zbyněk and Damborský, Jiří and Bosáková, Michaela}, keywords = {FGF2; Stem cells; Drugs}, language = {eng}, title = {Thermostable FGF2 polypeptide, use thereof}, url = {https://worldwide.espacenet.com/patent/search/family/054754475/publication/AU2016359722B2?q=pn%3DAU2016359722B2}, year = {2021} }
TY - PAT ID - 1845598 AU - Dvořák, Petr - Krejčí, Pavel - Bálek, Lukáš - Eiselleová, Lívia - Konečná, Žaneta - Dvořák, Pavel - Bednář, David - Brezovský, Jan - Šebestová, Eva - Chaloupková, Radka - Štěpánková, Veronika - Vaňáček, Pavel - Prokop, Zbyněk - Damborský, Jiří - Bosáková, Michaela PY - 2021 TI - Thermostable FGF2 polypeptide, use thereof KW - FGF2 KW - Stem cells KW - Drugs UR - https://worldwide.espacenet.com/patent/search/family/054754475/publication/AU2016359722B2?q=pn%3DAU2016359722B2 N2 - The invention provides an isolated thermostable polypeptide possessing FGF2 activity and having at least 85% sequence identity to SEQ ID NO: 2 (FGF2 wt) or a functional fragment thereof, and comprising at least one amino acid substitution R31L and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. Further it discloses a culture medium comprising subjected FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells. ER -
DVOŘÁK, Petr, Pavel KREJČÍ, Lukáš BÁLEK, Lívia EISELLEOVÁ, Žaneta KONEČNÁ, Pavel DVOŘÁK, David BEDNÁŘ, Jan BREZOVSKÝ, Eva ŠEBESTOVÁ, Radka CHALOUPKOVÁ, Veronika ŠTĚPÁNKOVÁ, Pavel VAŇÁČEK, Zbyněk PROKOP, Jiří DAMBORSKÝ and Michaela BOSÁKOVÁ. \textit{Thermostable FGF2 polypeptide, use thereof}. 2021.
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