J 2023

Depressive-like phenotype enhances relapse of nicotine seeking after forced abstinence in rats

AMCHOVÁ, Petra and Jana RUDÁ

Basic information

Original name

Depressive-like phenotype enhances relapse of nicotine seeking after forced abstinence in rats

Name in Czech

Depresi podobný fenotyp zvyšuje relaps vyhledávání nikotinu po období nucené abstinence u potkana

Authors

AMCHOVÁ, Petra (203 Czech Republic, belonging to the institution) and Jana RUDÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

The World Journal of Biological Psychiatry, OXON, TAYLOR & FRANCIS LTD, 2023, 1562-2975

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.100 in 2022

RIV identification code

RIV/00216224:14110/23:00129964

Organization unit

Faculty of Medicine

UT WoS

000796916600001

Keywords in English

abuse; depression; nicotine; olfactory bulbectomy; rats; self-administration

Tags

Tags

International impact, Reviewed
Změněno: 20/2/2023 10:14, Mgr. Tereza Miškechová

Abstract

V originále

Comorbidity of depression and drug addiction is common, but effective treatment is missing. A rat model combining the olfactory bulbectomy (OBX) model and IV drug self-administration has provided evidence of differential reactivity of the OBX rats towards drugs of abuse. This study evaluates nicotine taking and seeking behavior in this model.

Links

MUNI/A/1440/2021, interní kód MU
Name: Preklinický a klinický výzkum Farmakologického ústavu v oblasti farmakokinetiky, neurobiologie závislostí a personalizované farmakoterapie v onkologii (Acronym: Farm-Pre-Klin)
Investor: Masaryk University