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@article{1850959,
author = {Ožana, Veronika and Hruška, K. and Sechi, L.A.},
article_location = {Basel},
article_number = {7},
doi = {http://dx.doi.org/10.3390/ijms23073657},
keywords = {chronic inflammatory diseases; autoimmune diseases; T1D; nontuberculous mycobacteria; civilization diseases; civilization factors; global health problem; Mycobacterium avium subspecies paratuberculosis},
language = {eng},
issn = {1422-0067},
journal = {International Journal of Molecular Sciences},
title = {Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes},
url = {https://www.mdpi.com/1422-0067/23/7/3657/htm},
volume = {23},
year = {2022}
}
TY - JOUR
ID - 1850959
AU - Ožana, Veronika - Hruška, K. - Sechi, L.A.
PY - 2022
TI - Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes
JF - International Journal of Molecular Sciences
VL - 23
IS - 7
SP - 1-13
EP - 1-13
PB - MDPI
SN - 14220067
KW - chronic inflammatory diseases
KW - autoimmune diseases
KW - T1D
KW - nontuberculous mycobacteria
KW - civilization diseases
KW - civilization factors
KW - global health problem
KW - Mycobacterium avium subspecies paratuberculosis
UR - https://www.mdpi.com/1422-0067/23/7/3657/htm
N2 - Civilization factors are responsible for the increasing of human exposure to mycobacteria from environment, water, and food during the last few decades. Urbanization, lifestyle changes and new technologies in the animal and plant industry are involved in frequent contact of people with mycobacteria. Type 1 diabetes is a multifactorial polygenic disease; its origin is conditioned by the mutual interaction of genetic and other factors. The environmental factors and certain pathogenetic pathways are shared by some immune mediated chronic inflammatory and autoimmune diseases, which are associated with triggers originating mainly from Mycobacterium avium subspecies paratuberculosis, an intestinal pathogen which persists in the environment. Type 1 diabetes and some other chronic inflammatory diseases thus pose the global health problem which could be mitigated by measures aimed to decrease the human exposure to this neglected zoonotic mycobacterium.
ER -
OŽANA, Veronika, K. HRUŠKA and L.A. SECHI. Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes. \textit{International Journal of Molecular Sciences}. Basel: MDPI, 2022, vol.~23, No~7, p.~1-13. ISSN~1422-0067. Available from: https://dx.doi.org/10.3390/ijms23073657.
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