Neglected Facts on Mycobacterium Avium Subspecies
Paratuberculosis and Type 1 Diabetes

J 2022

Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes

OŽANA, Veronika, K. HRUŠKA and L.A. SECHI

Basic information

Original name

Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes

Authors

OŽANA, Veronika (203 Czech Republic, belonging to the institution), K. HRUŠKA (guarantor) and L.A. SECHI

Edition

International Journal of Molecular Sciences, Basel, MDPI, 2022, 1422-0067

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.600

RIV identification code

RIV/00216224:14160/22:00125760

Organization unit

Faculty of Pharmacy

DOI

http://dx.doi.org/10.3390/ijms23073657

UT WoS

000781092200001

Keywords in English

chronic inflammatory diseases; autoimmune diseases; T1D; nontuberculous mycobacteria; civilization diseases; civilization factors; global health problem; Mycobacterium avium subspecies paratuberculosis

Abstract

V originále

Civilization factors are responsible for the increasing of human exposure to mycobacteria from environment, water, and food during the last few decades. Urbanization, lifestyle changes and new technologies in the animal and plant industry are involved in frequent contact of people with mycobacteria. Type 1 diabetes is a multifactorial polygenic disease; its origin is conditioned by the mutual interaction of genetic and other factors. The environmental factors and certain pathogenetic pathways are shared by some immune mediated chronic inflammatory and autoimmune diseases, which are associated with triggers originating mainly from Mycobacterium avium subspecies paratuberculosis, an intestinal pathogen which persists in the environment. Type 1 diabetes and some other chronic inflammatory diseases thus pose the global health problem which could be mitigated by measures aimed to decrease the human exposure to this neglected zoonotic mycobacterium.

Citovat

OŽANA, Veronika, K. HRUŠKA and L.A. SECHI. Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes. International Journal of Molecular Sciences. Basel: MDPI, 2022, vol. 23, No 7, p. 1-13. ISSN 1422-0067. Available from: https://dx.doi.org/10.3390/ijms23073657.

@article{1850959,
   author = {Ožana, Veronika and Hruška, K. and Sechi, L.A.},
   article_location = {Basel},
   article_number = {7},
   doi = {http://dx.doi.org/10.3390/ijms23073657},
   keywords = {chronic inflammatory diseases; autoimmune diseases; T1D; nontuberculous mycobacteria; civilization diseases; civilization factors; global health problem; Mycobacterium avium subspecies paratuberculosis},
   language = {eng},
   issn = {1422-0067},
   journal = {International Journal of Molecular Sciences},
   title = {Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes},
   url = {https://www.mdpi.com/1422-0067/23/7/3657/htm},
   volume = {23},
   year = {2022}
}

TY  - JOUR
ID  - 1850959
AU  - Ožana, Veronika - Hruška, K. - Sechi, L.A.
PY  - 2022
TI  - Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes
JF  - International Journal of Molecular Sciences
VL  - 23
IS  - 7
SP  - 1-13
EP  - 1-13
PB  - MDPI
SN  - 14220067
KW  - chronic inflammatory diseases
KW  - autoimmune diseases
KW  - T1D
KW  - nontuberculous mycobacteria
KW  - civilization diseases
KW  - civilization factors
KW  - global health problem
KW  - Mycobacterium avium subspecies paratuberculosis
UR  - https://www.mdpi.com/1422-0067/23/7/3657/htm
N2  - Civilization factors are responsible for the increasing of human exposure to mycobacteria from environment, water, and food during the last few decades. Urbanization, lifestyle changes and new technologies in the animal and plant industry are involved in frequent contact of people with mycobacteria. Type 1 diabetes is a multifactorial polygenic disease; its origin is conditioned by the mutual interaction of genetic and other factors. The environmental factors and certain pathogenetic pathways are shared by some immune mediated chronic inflammatory and autoimmune diseases, which are associated with triggers originating mainly from Mycobacterium avium subspecies paratuberculosis, an intestinal pathogen which persists in the environment. Type 1 diabetes and some other chronic inflammatory diseases thus pose the global health problem which could be mitigated by measures aimed to decrease the human exposure to this neglected zoonotic mycobacterium.
ER  -

OŽANA, Veronika, K. HRUŠKA and L.A. SECHI. Neglected Facts on Mycobacterium Avium Subspecies Paratuberculosis and Type 1 Diabetes. \textit{International Journal of Molecular Sciences}. Basel: MDPI, 2022, vol.~23, No~7, p.~1-13. ISSN~1422-0067. Available from: https://dx.doi.org/10.3390/ijms23073657.

Detailed Information on Publication Record