ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE
CENTER STUDY

a 2022

ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE CENTER STUDY

POTRUSIL, Martin, Jan HLAVSA, Zdeněk KALA, Radek KROUPA, Hana KOLOVRATNÍKOVÁ et. al.

Basic information

Original name

ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE CENTER STUDY

Authors

POTRUSIL, Martin, Jan HLAVSA, Zdeněk KALA, Radek KROUPA, Hana KOLOVRATNÍKOVÁ, Dana SOCHOROVÁ, P. JANEČEK, Tomáš ANDRAŠINA and Lumír KUNOVSKÝ

Edition

ESGE Days 2022, 2022

Other information

Language

English

Type of outcome

Konferenční abstrakt

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 9.300

Organization unit

Faculty of Medicine

ISSN

DOI

http://dx.doi.org/10.1055/s-0042-1745261

Změněno: 5/5/2022 13:47, Mgr. Tereza Miškechová

Abstract

V originále

Aims Neoplastic tumors of the ampulla of Vater are rare. Pathologically benign lesions are primarily indicated for endoscopic treatment. Cases of early adenocarcinomas aff ecting only the mucosa might be resolved by endoscopic resection in selected patients. Tumors infi ltrating deeper layers of the wall must be removed by radical surgery. Methods In the years 2012 – 2020, 63 patients with ampullary tumors were treated at the University Hospital Brno. All underwent appropriate staging examinations. The individual therapeutic options were discussed by a multidisciplinary committee. The main monitored parameters were: the type of surgery, 30 day morbidity and mortality, the results of defi nitive histopathological examination, adjuvant therapy and recurrence of the disease. Results Surgical resection was indicated in 44 patients. Transduodenal ampullectomy (TDA) was performed in 11 patients. The main type of resection was pancreatoduodenectomy (PD) performed in 33 patients. 19 patients underwent endoscopic papillectomy. Defi nitive pathology described adenocarcinoma in 36 patients. Conclusions In the cases of adenomas of ampullary tumors endoscopic treatment is indicated. In early stages of ampullary carcinoma, it is appropriate to consider an endoscopic solution in selected patients. If endoscopic treatment is not possible due to the extent or biological nature of the lesion, a radical surgical solution with a preference for PD is fully indicated. TDA can be considered in polymorbid and elderly patients without suspected lymph node involvement. In all our patients with pT1a adenocarcinomas (n = 3), all nodes removed were pathologically negative. These patients could benefi t from endoscopic resection or TDA.

Citovat

POTRUSIL, Martin, Jan HLAVSA, Zdeněk KALA, Radek KROUPA, Hana KOLOVRATNÍKOVÁ, Dana SOCHOROVÁ, P. JANEČEK, Tomáš ANDRAŠINA and Lumír KUNOVSKÝ. ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE CENTER STUDY. In ESGE Days 2022. 2022. ISSN 0013-726X. Available from: https://dx.doi.org/10.1055/s-0042-1745261.

@proceedings{1851217,
   author = {Potrusil, Martin and Hlavsa, Jan and Kala, Zdeněk and Kroupa, Radek and Kolovratníková, Hana and Sochorová, Dana and Janeček, P. and Andrašina, Tomáš and Kunovský, Lumír},
   booktitle = {ESGE Days 2022},
   doi = {http://dx.doi.org/10.1055/s-0042-1745261},
   language = {eng},
   title = {ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE CENTER STUDY},
   year = {2022}
}

TY  - CONF
ID  - 1851217
AU  - Potrusil, Martin - Hlavsa, Jan - Kala, Zdeněk - Kroupa, Radek - Kolovratníková, Hana - Sochorová, Dana - Janeček, P. - Andrašina, Tomáš - Kunovský, Lumír
PY  - 2022
TI  - ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE CENTER STUDY
N2  - Aims Neoplastic tumors of the ampulla of Vater are rare. Pathologically benign lesions are primarily indicated for endoscopic treatment. Cases of early adenocarcinomas aff ecting only the mucosa might be resolved by endoscopic resection in selected patients. Tumors infi ltrating deeper layers of the wall must be removed by radical surgery. Methods In the years 2012 – 2020, 63 patients with ampullary tumors were treated at the University Hospital Brno. All underwent appropriate staging examinations. The individual therapeutic options were discussed by a multidisciplinary committee. The main monitored parameters were: the type of surgery, 30 day morbidity and mortality, the results of defi nitive histopathological examination, adjuvant therapy and recurrence of the disease. Results Surgical resection was indicated in 44 patients. Transduodenal ampullectomy (TDA) was performed in 11 patients. The main type of resection was pancreatoduodenectomy (PD) performed in 33 patients. 19 patients underwent endoscopic papillectomy. Defi nitive pathology described adenocarcinoma in 36 patients. Conclusions In the cases of adenomas of ampullary tumors endoscopic treatment is indicated. In early stages of ampullary carcinoma, it is appropriate to consider an endoscopic solution in selected patients. If endoscopic treatment is not possible due to the extent or biological nature of the lesion, a radical surgical solution with a preference for PD is fully indicated. TDA can be considered in polymorbid and elderly patients without suspected lymph node involvement. In all our patients with pT1a adenocarcinomas (n = 3), all nodes removed were pathologically negative. These patients could benefi t from endoscopic resection or TDA.
ER  -

POTRUSIL, Martin, Jan HLAVSA, Zdeněk KALA, Radek KROUPA, Hana KOLOVRATNÍKOVÁ, Dana SOCHOROVÁ, P. JANEČEK, Tomáš ANDRAŠINA and Lumír KUNOVSKÝ. ENDOSCOPIC AND SURGICAL TREATMENT OF AMPULLARY TUMORS: A SINGLE CENTER STUDY. In \textit{ESGE Days 2022}. 2022. ISSN~0013-726X. Available from: https://dx.doi.org/10.1055/s-0042-1745261.

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