Letter to the Editor concerning

J 2020

Letter to the Editor concerning "Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study" by Fritzell, P., Welinder-Olsson, C., Jonsson, B. et al. Eur Spine J (2019)

CAPOOR, Manu, A. MCDOWELL, C. BIRKENMAIER, externista FAHAD AHMED, E. COSCIA et. al.

Basic information

Original name

Letter to the Editor concerning "Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study" by Fritzell, P., Welinder-Olsson, C., Jonsson, B. et al. Eur Spine J (2019)

Authors

CAPOOR, Manu (840 United States of America, belonging to the institution), A. MCDOWELL, C. BIRKENMAIER, externista FAHAD AHMED (840 United States of America), E. COSCIA, A. RAZ, K. MAVROMMATI, V.A. FISCHETTI and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

EUROPEAN SPINE JOURNAL, 2020, 0940-6719

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.134

RIV identification code

RIV/00216224:14740/20:00124573

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1007/s00586-019-06237-1

UT WoS

000500348900006

Keywords in English

Back Pain; Bacteria; Humans; Intervertebral Disc Displacement; Leg

Abstract

V originále

We have read with interest the paper by Fritzell et al. which suggests the association of bacteria, especially the anaerobic bacterium Cutibacterium acnes (previously Propionibacterium acnes), with pain-generating degenerated discs is likely to reflect contamination arising from the skin. We find this view surprising given that the recent studies of Capoor et al. [1] and Ohrt-Nissen et al. [2] directly visualized C. acnes as a biofilm within surgically removed intervertebral disc tissue. Such observations are practically impossible to explain by contamination as this would require the contaminant to form a biofilm deep within a retrieved nucleus tissue fragment during the brief time between removal and freezing. Against this background, we would like to highlight a series of potential methodological limitations within the Fritzell et al. study that could impact on their final results and conclusions regarding the association of C. acnes with degenerated discs.

Citovat

CAPOOR, Manu, A. MCDOWELL, C. BIRKENMAIER, externista FAHAD AHMED, E. COSCIA, A. RAZ, K. MAVROMMATI, V.A. FISCHETTI and Ondřej SLABÝ. Letter to the Editor concerning "Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study" by Fritzell, P., Welinder-Olsson, C., Jonsson, B. et al. Eur Spine J (2019). EUROPEAN SPINE JOURNAL. 2020, vol. 29, No 3, p. 628-630. ISSN 0940-6719. Available from: https://dx.doi.org/10.1007/s00586-019-06237-1.

@article{1852566,
   author = {Capoor, Manu and McDowell, A. and Birkenmaier, C. and Fahad Ahmed, externista and Coscia, E. and Raz, A. and Mavrommati, K. and Fischetti, V.A. and Slabý, Ondřej},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s00586-019-06237-1},
   keywords = {Back Pain; Bacteria; Humans; Intervertebral Disc Displacement; Leg},
   language = {eng},
   issn = {0940-6719},
   journal = {EUROPEAN SPINE JOURNAL},
   title = {Letter to the Editor concerning "Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study" by Fritzell, P., Welinder-Olsson, C., Jonsson, B. et al. Eur Spine J (2019)},
   url = {https://link.springer.com/article/10.1007/s00586-019-06237-1},
   volume = {29},
   year = {2020}
}

TY  - JOUR
ID  - 1852566
AU  - Capoor, Manu - McDowell, A. - Birkenmaier, C. - Fahad Ahmed, externista - Coscia, E. - Raz, A. - Mavrommati, K. - Fischetti, V.A. - Slabý, Ondřej
PY  - 2020
TI  - Letter to the Editor concerning "Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study" by Fritzell, P., Welinder-Olsson, C., Jonsson, B. et al. Eur Spine J (2019)
JF  - EUROPEAN SPINE JOURNAL
VL  - 29
IS  - 3
SP  - 628-630
EP  - 628-630
SN  - 09406719
KW  - Back Pain
KW  - Bacteria
KW  - Humans
KW  - Intervertebral Disc Displacement
KW  - Leg
UR  - https://link.springer.com/article/10.1007/s00586-019-06237-1
N2  - We have read with interest the paper by Fritzell et al. which suggests the association of bacteria, especially the anaerobic bacterium Cutibacterium acnes (previously Propionibacterium acnes), with pain-generating degenerated discs is likely to reflect contamination arising from the skin. We find this view surprising given that the recent studies of Capoor et al. [1] and Ohrt-Nissen et al. [2] directly visualized C. acnes as a biofilm within surgically removed intervertebral disc tissue. Such observations are practically impossible to explain by contamination as this would require the contaminant to form a biofilm deep within a retrieved nucleus tissue fragment during the brief time between removal and freezing. Against this background, we would like to highlight a series of potential methodological limitations within the Fritzell et al. study that could impact on their final results and conclusions regarding the association of C. acnes with degenerated discs.
ER  -

CAPOOR, Manu, A. MCDOWELL, C. BIRKENMAIER, externista FAHAD AHMED, E. COSCIA, A. RAZ, K. MAVROMMATI, V.A. FISCHETTI and Ondřej SLABÝ. Letter to the Editor concerning ''Bacteria: back pain, leg pain and Modic sign: a surgical multicenter comparative study'' by Fritzell, P., Welinder-Olsson, C., Jonsson, B. et al. Eur Spine J (2019). \textit{EUROPEAN SPINE JOURNAL}. 2020, vol.~29, No~3, p.~628-630. ISSN~0940-6719. Available from: https://dx.doi.org/10.1007/s00586-019-06237-1.

Detailed Information on Publication Record