Autoři
DECKER, Barbora, Tomáš MLČOCH, Tomáš DOLEŽAL, Claudie CHARBONNEAU, Anita H. SUNG, Petra VOTHOVÁ, Pavol MAZAN a Sabina BILLOVÁ
V originále
Over a lifetime horizon, isavuconazole yields additional 0.30 QALYs (7.80 vs. 7.50) at the additional total cost of €3059 (€18,664 vs. €15,605) compared with SoC, with the incremental cost-effectiveness ratio of €10,251 per QALY. PSA showed that probability of isavuconazole to be cost-effective is 75% at the WTP threshold. OWSA and SA confirmed the robustness of the base-case result while the most influential parameters were mortality and prevalence of mucormycosis.