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@article{1853627,
author = {Mohamed, Lounis and Amir, Rais Mohammed and Djihad, Bencherit and Amir, Aouissi Hani and Adda, Oudjedi and Klugarová, Jitka and Pokorná, Andrea and Klugar, Miloslav and Riad, Abanoub},
article_location = {LAUSANNE},
article_number = {May 2022},
doi = {http://dx.doi.org/10.3389/fpubh.2022.896343},
keywords = {adenoviral-based vaccine; COVID-19; health workers; inactivated virus vaccine; side effects},
language = {eng},
issn = {2296-2565},
journal = {Frontiers in Public Health},
title = {Side Effects of COVID-19 Inactivated Virus vs. Adenoviral Vector Vaccines: Experience of Algerian Healthcare Workers},
url = {https://www.frontiersin.org/articles/10.3389/fpubh.2022.896343/full},
volume = {10},
year = {2022}
}
TY - JOUR
ID - 1853627
AU - Mohamed, Lounis - Amir, Rais Mohammed - Djihad, Bencherit - Amir, Aouissi Hani - Adda, Oudjedi - Klugarová, Jitka - Pokorná, Andrea - Klugar, Miloslav - Riad, Abanoub
PY - 2022
TI - Side Effects of COVID-19 Inactivated Virus vs. Adenoviral Vector Vaccines: Experience of Algerian Healthcare Workers
JF - Frontiers in Public Health
VL - 10
IS - May 2022
SP - 1-12
EP - 1-12
PB - FRONTIERS MEDIA SA
SN - 22962565
KW - adenoviral-based vaccine
KW - COVID-19
KW - health workers
KW - inactivated virus vaccine
KW - side effects
UR - https://www.frontiersin.org/articles/10.3389/fpubh.2022.896343/full
N2 - Healthcare workers were prioritized in vaccination campaigns globally because they are exposed to the highest risk of contamination by SARS-CoV-2. This study evaluated the self-reported post-vaccination side effects of inactivated (BBIBP-CorV and CoronaVac) and adenoviral vector-based (AZD1222, Gam-COVID-Vac and Ad26.COV2.S) vaccines among Algerian healthcare workers using a validated questionnaire. The final analysis included 721 healthcare workers, with a predominance of females (59.1%) and younger individuals 20–30 years old (39.4%). Less than half (49.1%) of the respondents reported at least one local side effect, while 53.8% reported at least one systemic side effect. These side effects were more prevalent among viral vector vaccinees than inactivated virus vaccinees. The most common local side effects were injection site pain (39%) and arm pain (25.4%), while fatigue (34.4%), fever (28.4%), headache (24.8%) and myalgia (22.7%) were the most prevalent systemic side effects. The side effects appeared earlier among inactivated virus vaccines recipients and generally lasted for 2 to 3 days for the two vaccinated groups. The risk factors associated with a higher prevalence of side effects included female gender, allergic individuals, individuals with regular medication, those who contracted the COVID-19 disease and those who received two doses for both inactivated and viral-based vaccines groups. Despite the higher prevalence of post-vaccination side effects among adenoviral vector vaccines recipients, both vaccines groups were equally effective in preventing symptomatic infections, and no life-threatening side effects were reported in either vaccine group.
ER -
MOHAMED, Lounis, Rais Mohammed AMIR, Bencherit DJIHAD, Aouissi Hani AMIR, Oudjedi ADDA, Jitka KLUGAROVÁ, Andrea POKORNÁ, Miloslav KLUGAR and Abanoub RIAD. Side Effects of COVID-19 Inactivated Virus vs. Adenoviral Vector Vaccines: Experience of Algerian Healthcare Workers. \textit{Frontiers in Public Health}. LAUSANNE: FRONTIERS MEDIA SA, 2022, vol.~10, May 2022, p.~1-12. ISSN~2296-2565. Available from: https://dx.doi.org/10.3389/fpubh.2022.896343.
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