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@proceedings{1854279,
author = {Chocholová, Eva and Drozdová, Eva and Fialová, Dana and Černý, Martin and Zwinsová, Barbora and Vídeňská, Petra and Brzobohatá, Kristýna and Novotná, Kateřina},
booktitle = {The Biomania Student Scientific Meeting 2022},
keywords = {ancient DNA; aDNA; rare disease; rare infectious disease; pathogen; dental calculus; metagenomics},
language = {eng},
isbn = {978-80-280-0040-0},
title = {Metagenomic research of the ancient human dental calculus as a potential source for the study of rare infectious diseases},
year = {2022}
}
TY - CONF
ID - 1854279
AU - Chocholová, Eva - Drozdová, Eva - Fialová, Dana - Černý, Martin - Zwinsová, Barbora - Vídeňská, Petra - Brzobohatá, Kristýna - Novotná, Kateřina
PY - 2022
TI - Metagenomic research of the ancient human dental calculus as a potential source for the study of rare infectious diseases
SN - 9788028000400
KW - ancient DNA
KW - aDNA
KW - rare disease
KW - rare infectious disease
KW - pathogen
KW - dental calculus
KW - metagenomics
N2 - Ancient human dental calculus has been intensively studied in recent years by diverse molecular methods. It was found to be a rich and important source for detailed study of past populations, as well as their pathogens. This study presents the results of metagenomic research by sequencing 16S rRNA gene from bacteria trapped inside tartar and suggests the possibility of using such an approach to screen samples for rare infectious diseases. Dental calculus samples came from populations of four different periods: Copper Age (Funnelbeaker culture), Bronze Age (Unetice), Middle Ages (Great Moravia), and early modern period, which provides a comparison. Genera found include Nocardia, Haemophilus, Bartonella, Shigella, or Neisseria. Applied approach is recommended as a robust screening method. All laboratory procedures were carried out in a dedicated ancient biomolecule facility of the Laboratory of Biological and Molecular Anthropology.
ER -
CHOCHOLOVÁ, Eva, Eva DROZDOVÁ, Dana FIALOVÁ, Martin ČERNÝ, Barbora ZWINSOVÁ, Petra VÍDEŇSKÁ, Kristýna BRZOBOHATÁ and Kateřina NOVOTNÁ. Metagenomic research of the ancient human dental calculus as a potential source for the study of rare infectious diseases. In \textit{The Biomania Student Scientific Meeting 2022}. 2022. ISBN~978-80-280-0040-0.
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