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@article{1863220, author = {López Cabeza, María del Rocío and Kah, Melanie and Grillo, Renato and Koutny, Marek and Salac, Jan and Bílková, Zuzana and Eghbalinejad, Mahleh and Hofman, Jakub}, article_location = {CAMBRIDGE}, article_number = {4}, doi = {http://dx.doi.org/10.1039/d1en00981h}, keywords = {LIPID CARRIERS NLC; DRUG-RELEASE; NANOPARTICLES; MECHANISMS; PESTICIDES; DELIVERY; OIL}, language = {eng}, issn = {2051-8153}, journal = {Environmental Science: Nano}, title = {Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics}, url = {https://pubs.rsc.org/en/content/articlelanding/2022/EN/D1EN00981H}, volume = {9}, year = {2022} }
TY - JOUR ID - 1863220 AU - López Cabeza, María del Rocío - Kah, Melanie - Grillo, Renato - Koutny, Marek - Salac, Jan - Bílková, Zuzana - Eghbalinejad, Mahleh - Hofman, Jakub PY - 2022 TI - Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics JF - Environmental Science: Nano VL - 9 IS - 4 SP - 1427-1438 EP - 1427-1438 PB - ROYAL SOC CHEMISTRY SN - 20518153 KW - LIPID CARRIERS NLC KW - DRUG-RELEASE KW - NANOPARTICLES KW - MECHANISMS KW - PESTICIDES KW - DELIVERY KW - OIL UR - https://pubs.rsc.org/en/content/articlelanding/2022/EN/D1EN00981H N2 - In this work, tebuconazole and terbuthylazine were encapsulated in nanocarriers prepared from the polymers poly-epsilon-caprolactone, poly(3-hydroxybutyrate) and poly(acrylic acid)/polylactide, and in a nanostructured lipid carrier. The release kinetics of the prepared nanoformulations was assessed by the dialysis method and the results obtained from these release experiments were related to the durability of the nanoformulations. The outcomes suggested that the release of the active ingredients in these nanoformulations depended mainly on the interaction between the nanocarrier materials and the pesticides. In addition, it was found that the durability of the complex formed by tebuconazole encapsulated in poly(3-hydroxybutyrate) was affected by its dilution, the durability being shorter with the increase of dilution factor. The findings in this work could help the design of pesticide nanoformulations with certain durability according to the pesticide doses required in the field by selecting the appropriate nanocarrier material. Likewise, the results indicate the need to evaluate the release kinetics of the active ingredients under dilution of the nanoformulations, since the dilution in the mixing tank before application or in the soil during irrigation or rainfall events could influence the durability of the nanoformulations and as a consequence, their environmental risk assessment. ER -
LÓPEZ CABEZA, María del Rocío, Melanie KAH, Renato GRILLO, Marek KOUTNY, Jan SALAC, Zuzana BÍLKOVÁ, Mahleh EGHBALINEJAD and Jakub HOFMAN. Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics. \textit{Environmental Science: Nano}. CAMBRIDGE: ROYAL SOC CHEMISTRY, 2022, vol.~9, No~4, p.~1427-1438. ISSN~2051-8153. Available from: https://dx.doi.org/10.1039/d1en00981h.
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