LÓPEZ CABEZA, María del Rocío, Melanie KAH, Renato GRILLO, Marek KOUTNY, Jan SALAC, Zuzana BÍLKOVÁ, Mahleh EGHBALINEJAD and Jakub HOFMAN. Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics. Environmental Science: Nano. CAMBRIDGE: ROYAL SOC CHEMISTRY, 2022, vol. 9, No 4, p. 1427-1438. ISSN 2051-8153. Available from: https://dx.doi.org/10.1039/d1en00981h.
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Basic information
Original name Tebuconazole and terbuthylazine encapsulated in nanocarriers: preparation, characterization and release kinetics
Authors LÓPEZ CABEZA, María del Rocío (724 Spain, belonging to the institution), Melanie KAH, Renato GRILLO, Marek KOUTNY, Jan SALAC, Zuzana BÍLKOVÁ (203 Czech Republic, belonging to the institution), Mahleh EGHBALINEJAD (364 Islamic Republic of Iran, belonging to the institution) and Jakub HOFMAN (203 Czech Republic, guarantor, belonging to the institution).
Edition Environmental Science: Nano, CAMBRIDGE, ROYAL SOC CHEMISTRY, 2022, 2051-8153.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10511 Environmental sciences
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 7.300
RIV identification code RIV/00216224:14310/22:00126162
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1039/d1en00981h
UT WoS 000762375900001
Keywords in English LIPID CARRIERS NLC; DRUG-RELEASE; NANOPARTICLES; MECHANISMS; PESTICIDES; DELIVERY; OIL
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Michaela Hylsová, Ph.D., učo 211937. Changed: 28/6/2022 22:07.
Abstract
In this work, tebuconazole and terbuthylazine were encapsulated in nanocarriers prepared from the polymers poly-epsilon-caprolactone, poly(3-hydroxybutyrate) and poly(acrylic acid)/polylactide, and in a nanostructured lipid carrier. The release kinetics of the prepared nanoformulations was assessed by the dialysis method and the results obtained from these release experiments were related to the durability of the nanoformulations. The outcomes suggested that the release of the active ingredients in these nanoformulations depended mainly on the interaction between the nanocarrier materials and the pesticides. In addition, it was found that the durability of the complex formed by tebuconazole encapsulated in poly(3-hydroxybutyrate) was affected by its dilution, the durability being shorter with the increase of dilution factor. The findings in this work could help the design of pesticide nanoformulations with certain durability according to the pesticide doses required in the field by selecting the appropriate nanocarrier material. Likewise, the results indicate the need to evaluate the release kinetics of the active ingredients under dilution of the nanoformulations, since the dilution in the mixing tank before application or in the soil during irrigation or rainfall events could influence the durability of the nanoformulations and as a consequence, their environmental risk assessment.
Links
EF17_043/0009632, research and development projectName: CETOCOEN Excellence
GA18-19324S, research and development projectName: Nanopesticidy v životním prostředí – porozumění jejich osudu, biodostupnosti, účinkům a rizikům v půdě a vodě
Investor: Czech Science Foundation
LM2018121, research and development projectName: Výzkumná infrastruktura RECETOX (Acronym: RECETOX RI)
Investor: Ministry of Education, Youth and Sports of the CR, RECETOX RI
857560, interní kód MU
(CEP code: EF17_043/0009632)
Name: CETOCOEN Excellence (Acronym: CETOCOEN Excellence)
Investor: European Union, Spreading excellence and widening participation
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