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@article{1874317,
author = {Vaculová, Jitka and Kroupa, Radek and Kala, Zdeněk and Dolina, Jiří and Grolich, Tomáš and Vlažný, Jakub and Said, Dávid and Izakovičová Hollá, Lydie and Bořilová Linhartová, Petra and Procházka, Vladimír and Joukal, Marek and Jabandžiev, Petr and Slabý, Ondřej and Kunovský, Lumír},
article_location = {Basel},
article_number = {7},
doi = {http://dx.doi.org/10.3390/diagnostics12071616},
keywords = {confocal laser endomicroscopy; probe-based confocal laser endomicroscopy; diagnosis; Barrett’s esophagus; esophageal cancer; early esophageal adenocarcinoma},
language = {eng},
issn = {2075-4418},
journal = {Diagnostics},
title = {The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma},
url = {https://www.mdpi.com/2075-4418/12/7/1616},
volume = {12},
year = {2022}
}
TY - JOUR
ID - 1874317
AU - Vaculová, Jitka - Kroupa, Radek - Kala, Zdeněk - Dolina, Jiří - Grolich, Tomáš - Vlažný, Jakub - Said, Dávid - Izakovičová Hollá, Lydie - Bořilová Linhartová, Petra - Procházka, Vladimír - Joukal, Marek - Jabandžiev, Petr - Slabý, Ondřej - Kunovský, Lumír
PY - 2022
TI - The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma
JF - Diagnostics
VL - 12
IS - 7
SP - 1-12
EP - 1-12
PB - MDPI
SN - 20754418
KW - confocal laser endomicroscopy
KW - probe-based confocal laser endomicroscopy
KW - diagnosis
KW - Barrett’s esophagus
KW - esophageal cancer
KW - early esophageal adenocarcinoma
UR - https://www.mdpi.com/2075-4418/12/7/1616
N2 - Confocal laser endomicroscopy (CLE) is a diagnostic technique that enables real-time microscopic imaging during microscopic examination and evaluation of epithelial structures with 1000-fold magnification. CLE can be used in the diagnosis of various pathologies, in pneumology, and in urology, and it is very widely utilized in gastroenterology, most importantly in the diagnosis of Barrett’s esophagus (BE), esophageal adenocarcinoma (EAC), biliary strictures, and cystic pancreatic lesions. A literature search was made in MEDLINE/PubMed and Google Scholar databases while focusing on diagnostics using CLE of BE and EAC. We then examined randomized and observational studies, systematic reviews, and meta-analyses relating to the utilization of CLE in BE and EAC diagnostics. Here, we discuss whether CLE can be a suitable diagnostic method for surveillance of BE. Even though many studies have proven that CLE increases diagnostic accuracy in detecting neoplastic transformation of BE, CLE is still not used as a standard diagnostic tool in BE surveillance due to a deficiency of scientific evidence. More studies and data are needed if CLE is to find a place as a new technique in BE surveillance.
ER -
VACULOVÁ, Jitka, Radek KROUPA, Zdeněk KALA, Jiří DOLINA, Tomáš GROLICH, Jakub VLAŽNÝ, Dávid SAID, Lydie IZAKOVIČOVÁ HOLLÁ, Petra BOŘILOVÁ LINHARTOVÁ, Vladimír PROCHÁZKA, Marek JOUKAL, Petr JABANDŽIEV, Ondřej SLABÝ and Lumír KUNOVSKÝ. The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma. \textit{Diagnostics}. Basel: MDPI, 2022, vol.~12, No~7, p.~1-12. ISSN~2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics12071616.
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