The Use of Confocal Laser Endomicroscopy in Diagnosing
Barrett’s Esophagus and Esophageal Adenocarcinoma

J 2022

The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma

VACULOVÁ, Jitka, Radek KROUPA, Zdeněk KALA, Jiří DOLINA, Tomáš GROLICH et. al.

Basic information

Original name

The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma

Authors

VACULOVÁ, Jitka (203 Czech Republic, belonging to the institution), Radek KROUPA (203 Czech Republic, belonging to the institution), Zdeněk KALA (203 Czech Republic, belonging to the institution), Jiří DOLINA (203 Czech Republic, belonging to the institution), Tomáš GROLICH (203 Czech Republic, belonging to the institution), Jakub VLAŽNÝ (203 Czech Republic, belonging to the institution), Dávid SAID (703 Slovakia, belonging to the institution), Lydie IZAKOVIČOVÁ HOLLÁ (203 Czech Republic, belonging to the institution), Petra BOŘILOVÁ LINHARTOVÁ (203 Czech Republic, belonging to the institution), Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution), Marek JOUKAL (203 Czech Republic, belonging to the institution), Petr JABANDŽIEV (203 Czech Republic, belonging to the institution), Ondřej SLABÝ (203 Czech Republic, belonging to the institution) and Lumír KUNOVSKÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Diagnostics, Basel, MDPI, 2022, 2075-4418

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30219 Gastroenterology and hepatology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.600

RIV identification code

RIV/00216224:14110/22:00129673

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3390/diagnostics12071616

UT WoS

000832278900001

Keywords in English

confocal laser endomicroscopy; probe-based confocal laser endomicroscopy; diagnosis; Barrett’s esophagus; esophageal cancer; early esophageal adenocarcinoma

Abstract

V originále

Confocal laser endomicroscopy (CLE) is a diagnostic technique that enables real-time microscopic imaging during microscopic examination and evaluation of epithelial structures with 1000-fold magnification. CLE can be used in the diagnosis of various pathologies, in pneumology, and in urology, and it is very widely utilized in gastroenterology, most importantly in the diagnosis of Barrett’s esophagus (BE), esophageal adenocarcinoma (EAC), biliary strictures, and cystic pancreatic lesions. A literature search was made in MEDLINE/PubMed and Google Scholar databases while focusing on diagnostics using CLE of BE and EAC. We then examined randomized and observational studies, systematic reviews, and meta-analyses relating to the utilization of CLE in BE and EAC diagnostics. Here, we discuss whether CLE can be a suitable diagnostic method for surveillance of BE. Even though many studies have proven that CLE increases diagnostic accuracy in detecting neoplastic transformation of BE, CLE is still not used as a standard diagnostic tool in BE surveillance due to a deficiency of scientific evidence. More studies and data are needed if CLE is to find a place as a new technique in BE surveillance.

Links

NU20-03-00126, research and development project

Name: Hostitelský mikrobiom ve vztahu k rozvoji Barrettova jícnu a adenokarcinomu jícnu

Investor: Ministry of Health of the CR, Host microbiome in relation to Barrett ́s esophagus and esophageal adenocarcinoma development, Subprogram 1 - standard

Citovat

VACULOVÁ, Jitka, Radek KROUPA, Zdeněk KALA, Jiří DOLINA, Tomáš GROLICH, Jakub VLAŽNÝ, Dávid SAID, Lydie IZAKOVIČOVÁ HOLLÁ, Petra BOŘILOVÁ LINHARTOVÁ, Vladimír PROCHÁZKA, Marek JOUKAL, Petr JABANDŽIEV, Ondřej SLABÝ and Lumír KUNOVSKÝ. The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma. Diagnostics. Basel: MDPI, 2022, vol. 12, No 7, p. 1-12. ISSN 2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics12071616.

@article{1874317,
   author = {Vaculová, Jitka and Kroupa, Radek and Kala, Zdeněk and Dolina, Jiří and Grolich, Tomáš and Vlažný, Jakub and Said, Dávid and Izakovičová Hollá, Lydie and Bořilová Linhartová, Petra and Procházka, Vladimír and Joukal, Marek and Jabandžiev, Petr and Slabý, Ondřej and Kunovský, Lumír},
   article_location = {Basel},
   article_number = {7},
   doi = {http://dx.doi.org/10.3390/diagnostics12071616},
   keywords = {confocal laser endomicroscopy; probe-based confocal laser endomicroscopy; diagnosis; Barrett’s esophagus; esophageal cancer; early esophageal adenocarcinoma},
   language = {eng},
   issn = {2075-4418},
   journal = {Diagnostics},
   title = {The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma},
   url = {https://www.mdpi.com/2075-4418/12/7/1616},
   volume = {12},
   year = {2022}
}

TY  - JOUR
ID  - 1874317
AU  - Vaculová, Jitka - Kroupa, Radek - Kala, Zdeněk - Dolina, Jiří - Grolich, Tomáš - Vlažný, Jakub - Said, Dávid - Izakovičová Hollá, Lydie - Bořilová Linhartová, Petra - Procházka, Vladimír - Joukal, Marek - Jabandžiev, Petr - Slabý, Ondřej - Kunovský, Lumír
PY  - 2022
TI  - The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma
JF  - Diagnostics
VL  - 12
IS  - 7
SP  - 1-12
EP  - 1-12
PB  - MDPI
SN  - 20754418
KW  - confocal laser endomicroscopy
KW  - probe-based confocal laser endomicroscopy
KW  - diagnosis
KW  - Barrett’s esophagus
KW  - esophageal cancer
KW  - early esophageal adenocarcinoma
UR  - https://www.mdpi.com/2075-4418/12/7/1616
N2  - Confocal laser endomicroscopy (CLE) is a diagnostic technique that enables real-time microscopic imaging during microscopic examination and evaluation of epithelial structures with 1000-fold magnification. CLE can be used in the diagnosis of various pathologies, in pneumology, and in urology, and it is very widely utilized in gastroenterology, most importantly in the diagnosis of Barrett’s esophagus (BE), esophageal adenocarcinoma (EAC), biliary strictures, and cystic pancreatic lesions. A literature search was made in MEDLINE/PubMed and Google Scholar databases while focusing on diagnostics using CLE of BE and EAC. We then examined randomized and observational studies, systematic reviews, and meta-analyses relating to the utilization of CLE in BE and EAC diagnostics. Here, we discuss whether CLE can be a suitable diagnostic method for surveillance of BE. Even though many studies have proven that CLE increases diagnostic accuracy in detecting neoplastic transformation of BE, CLE is still not used as a standard diagnostic tool in BE surveillance due to a deficiency of scientific evidence. More studies and data are needed if CLE is to find a place as a new technique in BE surveillance.
ER  -

VACULOVÁ, Jitka, Radek KROUPA, Zdeněk KALA, Jiří DOLINA, Tomáš GROLICH, Jakub VLAŽNÝ, Dávid SAID, Lydie IZAKOVIČOVÁ HOLLÁ, Petra BOŘILOVÁ LINHARTOVÁ, Vladimír PROCHÁZKA, Marek JOUKAL, Petr JABANDŽIEV, Ondřej SLABÝ and Lumír KUNOVSKÝ. The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett’s Esophagus and Esophageal Adenocarcinoma. \textit{Diagnostics}. Basel: MDPI, 2022, vol.~12, No~7, p.~1-12. ISSN~2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics12071616.

Detailed Information on Publication Record