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@article{1874647,
author = {Bosch, J. and Pearce, L. A. and Sharma, M. and Mikulík, Robert and Whiteley, W. N. and Canavan, M. and Hart, R. G. and Donnellg, M. J.},
article_location = {AMSTERDAM},
article_number = {4},
doi = {http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106329},
keywords = {Functional scale; Embolic strokes of undetermined source; ESUS; Clinical trial},
language = {eng},
issn = {1052-3057},
journal = {JOURNAL OF STROKE & CEREBROVASCULAR DISEASES},
title = {Functional Abilities of an International Post-Stroke Population: Standard Assessment of Global Everyday Activities (SAGEA) Scale},
url = {https://www.sciencedirect.com/science/article/pii/S105230572200026X?via%3Dihub},
volume = {31},
year = {2022}
}
TY - JOUR
ID - 1874647
AU - Bosch, J. - Pearce, L. A. - Sharma, M. - Mikulík, Robert - Whiteley, W. N. - Canavan, M. - Hart, R. G. - Donnellg, M. J.
PY - 2022
TI - Functional Abilities of an International Post-Stroke Population: Standard Assessment of Global Everyday Activities (SAGEA) Scale
JF - JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
VL - 31
IS - 4
SP - 1-8
EP - 1-8
PB - ELSEVIER SCIENCE BV
SN - 10523057
KW - Functional scale
KW - Embolic strokes of undetermined source
KW - ESUS
KW - Clinical trial
UR - https://www.sciencedirect.com/science/article/pii/S105230572200026X?via%3Dihub
N2 - Background and Objectives: Function is an important outcome after stroke; traditional assessments may not capture functional deficits important to patients. We examined the validity of the Standard Assessment of Global Everyday Activities (SAGEA), a patient-reported outcome that assesses activities important to patients and for use in international clinical trials. Methods: The NAVIGATE-ESUS trial evaluated rivaroxaban compared to aspirin in preventing recurrent stroke in 7213 participants. The Modified Rankin Scale (mRS), the National Institutes of Health Stroke Scale (NIHSS), and the SAGEA were collected at entry. Chi square tests were used to compare proportions and Spearman rank correlations were used to compare between measures. SAGEA was compared to the Modified Frailty Index (MFI) and the occurrence of infarct to examine criterion validity Results: Participants were 67 years, 2/3 were male, and at baseline 30% had no disability and 58% had slight disability according to mRS scores. SAGEA was weakly correlated with the mRS (r=0.37), the NIHSS (r=0.29) and the MFI (r=0.30). Of the 2154 with an mRS score of 0, 61% reported difficulty on the SAGEA. The largest discrepancies between SAGEA and other measures were because of cognitive functional deficits detected by the SAGEA that were not identified on other assessments. A larger number of MRI identified infarcts (acute and covert) were associated with a higher SAGEA score (p=0.007). Conclusions: The SAGEA is a simple, globally applicable measure of cognitive and functional abilities that identifies issues that other commonly used assessments of disability and function do not capture.
ER -
BOSCH, J., L. A. PEARCE, M. SHARMA, Robert MIKULÍK, W. N. WHITELEY, M. CANAVAN, R. G. HART and M. J. DONNELLG. Functional Abilities of an International Post-Stroke Population: Standard Assessment of Global Everyday Activities (SAGEA) Scale. \textit{JOURNAL OF STROKE \&{} CEREBROVASCULAR DISEASES}. AMSTERDAM: ELSEVIER SCIENCE BV, 2022, vol.~31, No~4, p.~1-8. ISSN~1052-3057. Available from: https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106329.
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