Prevention of sarcopenia in patients with obesity after
bariatric and metabolic surgery: the effect of programmed
training on the muscle tissue and anthropometric functions – a
randomized controlled trial (SarxOb study protocol).

J 2023

Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: the effect of programmed training on the muscle tissue and anthropometric functions – a randomized controlled trial (SarxOb study protocol).

BUŽGA, Marek, Matej PEKAŘ, Jaroslav UCHYTIL, Veronika HORKÁ, Jan MALŮŠ et. al.

Basic information

Original name

Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: the effect of programmed training on the muscle tissue and anthropometric functions – a randomized controlled trial (SarxOb study protocol).

Authors

BUŽGA, Marek (203 Czech Republic), Matej PEKAŘ (703 Slovakia, guarantor, belonging to the institution), Jaroslav UCHYTIL (203 Czech Republic), Veronika HORKÁ (203 Czech Republic), Jan MALŮŠ (203 Czech Republic), Dominik VILÍMEK (203 Czech Republic), Zdeněk ŠVAGERA (203 Czech Republic), Petr KUTÁČ (203 Czech Republic) and Pavol HOLÉCZY (703 Slovakia)

Edition

BIOMOLECULES AND BIOMEDICINE, SARAJEVO, ASSOC BASIC MEDICAL SCI FEDERATION BOSNIA & HERZEGOVINA SARAJEVO, 2023, 2831-0896

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

Bosnia and Herzegovina

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

RIV identification code

RIV/00216224:14110/23:00129990

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.17305/bjbms.2022.7786

UT WoS

000957261000002

Keywords (in Czech)

Sarcopenia; exercise; bariatric; metabolic; surgery

Keywords in English

Sarcopenia; exercise; bariatric; metabolic; surgery

Abstract

V originále

Obesity is a serious metabolic disease that significantly increases cardiovascular risks and other health complications. Sarcopenia is an independent risk factor for morbidity and mortality in patients suffering from obesity that increases the health risks and is associated with cardiac, respiratory and other diseases. Bariatric and metabolic surgery (BMS) leads to significant changes in body composition. Our pilot study showed that bariatric patients are at risk of sarcopenia after BMS. This finding resulted in a hypothesis that an exercise plan in the experimental group will lead to postural stabilization and a lower decline in muscle homotopy, further leading to a greater reduction in fat mass and a positive effect of exercise on skeletal muscle volume and strength and endocrine-metabolic function. The aim of the present study is to determine the effect of programmed aerobic and strength training on muscle function, volume, and morphology in patients after BMS. The study is a single-center, randomized clinical trial after sleeve gastrectomy focused on muscle tissue. The experimental group will perform targeted physical activity once a week for 12 months and the training plan will include anaerobic and aerobic components. Magnetic resonance imaging of skeletal muscles will be correlated with the values of densitometry examination and changes in body composition, certain blood parameters of myokines, biomechanical analysis of movement abnormalities, and behavioral and dietary counseling. This study will address the research questions about the effect of programmed training on muscle tissue and muscular functions after BMS.

Links

MUNI/A/1133/2021, interní kód MU

Name: Od buňky k medicíně (Acronym: CELLVIEW)

Investor: Masaryk University

Citovat

BUŽGA, Marek, Matej PEKAŘ, Jaroslav UCHYTIL, Veronika HORKÁ, Jan MALŮŠ, Dominik VILÍMEK, Zdeněk ŠVAGERA, Petr KUTÁČ and Pavol HOLÉCZY. Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: the effect of programmed training on the muscle tissue and anthropometric functions – a randomized controlled trial (SarxOb study protocol). BIOMOLECULES AND BIOMEDICINE. SARAJEVO: ASSOC BASIC MEDICAL SCI FEDERATION BOSNIA & HERZEGOVINA SARAJEVO, 2023, vol. 23, No 2, p. 191-197. ISSN 2831-0896. Available from: https://dx.doi.org/10.17305/bjbms.2022.7786.

@article{1875641,
   author = {Bužga, Marek and Pekař, Matej and Uchytil, Jaroslav and Horká, Veronika and Malůš, Jan and Vilímek, Dominik and Švagera, Zdeněk and Kutáč, Petr and Holéczy, Pavol},
   article_location = {SARAJEVO},
   article_number = {2},
   doi = {http://dx.doi.org/10.17305/bjbms.2022.7786},
   keywords = {Sarcopenia; exercise; bariatric; metabolic; surgery},
   language = {eng},
   issn = {2831-0896},
   journal = {BIOMOLECULES AND BIOMEDICINE},
   title = {Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: the effect of programmed training on the muscle tissue and anthropometric functions – a randomized controlled trial (SarxOb study protocol).},
   url = {https://doi.org/10.17305/bjbms.2022.7786},
   volume = {23},
   year = {2023}
}

TY  - JOUR
ID  - 1875641
AU  - Bužga, Marek - Pekař, Matej - Uchytil, Jaroslav - Horká, Veronika - Malůš, Jan - Vilímek, Dominik - Švagera, Zdeněk - Kutáč, Petr - Holéczy, Pavol
PY  - 2023
TI  - Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: the effect of programmed training on the muscle tissue and anthropometric functions – a randomized controlled trial (SarxOb study protocol).
JF  - BIOMOLECULES AND BIOMEDICINE
VL  - 23
IS  - 2
SP  - 191-197
EP  - 191-197
PB  - ASSOC BASIC MEDICAL SCI FEDERATION BOSNIA & HERZEGOVINA SARAJEVO
SN  - 28310896
KW  - Sarcopenia
KW  - exercise
KW  - bariatric
KW  - metabolic
KW  - surgery
UR  - https://doi.org/10.17305/bjbms.2022.7786
N2  - Obesity is a serious metabolic disease that significantly increases cardiovascular risks and other health complications. Sarcopenia is an independent risk factor for morbidity and mortality in patients suffering from obesity that increases the health risks and is associated with cardiac, respiratory and other diseases. Bariatric and metabolic surgery (BMS) leads to significant changes in body composition. Our pilot study showed that bariatric patients are at risk of sarcopenia after BMS. This finding resulted in a hypothesis that an exercise plan in the experimental group will lead to postural stabilization and a lower decline in muscle homotopy, further leading to a greater reduction in fat mass and a positive effect of exercise on skeletal muscle volume and strength and endocrine-metabolic function. The aim of the present study is to determine the effect of programmed aerobic and strength training on muscle function, volume, and morphology in patients after BMS. The study is a single-center, randomized clinical trial after sleeve gastrectomy focused on muscle tissue. The experimental group will perform targeted physical activity once a week for 12 months and the training plan will include anaerobic and aerobic components. Magnetic resonance imaging of skeletal muscles will be correlated with the values of densitometry examination and changes in body composition, certain blood parameters of myokines, biomechanical analysis of movement abnormalities, and behavioral and dietary counseling. This study will address the research questions about the effect of programmed training on muscle tissue and muscular functions after BMS.
ER  -

BUŽGA, Marek, Matej PEKAŘ, Jaroslav UCHYTIL, Veronika HORKÁ, Jan MALŮŠ, Dominik VILÍMEK, Zdeněk ŠVAGERA, Petr KUTÁČ and Pavol HOLÉCZY. Prevention of sarcopenia in patients with obesity after bariatric and metabolic surgery: the effect of programmed training on the muscle tissue and anthropometric functions – a randomized controlled trial (SarxOb study protocol). \textit{BIOMOLECULES AND BIOMEDICINE}. SARAJEVO: ASSOC BASIC MEDICAL SCI FEDERATION BOSNIA \&{} HERZEGOVINA SARAJEVO, 2023, vol.~23, No~2, p.~191-197. ISSN~2831-0896. Available from: https://dx.doi.org/10.17305/bjbms.2022.7786.

Detailed Information on Publication Record