PÍŽOVÁ, Hana, Milan MALANÍK, Karel ŠMEJKAL, Michal ORAVEC and Pavel BOBÁĽ. Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents. RSC Advances. Cambridge: Royal Society of Chemistry, 2022, vol. 12, No 13, p. 8188-8192. ISSN 2046-2069. Available from: https://dx.doi.org/10.1039/d2ra00441k.
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Basic information
Original name Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents
Authors PÍŽOVÁ, Hana (203 Czech Republic, belonging to the institution), Milan MALANÍK (203 Czech Republic, belonging to the institution), Karel ŠMEJKAL (203 Czech Republic, belonging to the institution), Michal ORAVEC and Pavel BOBÁĽ (703 Slovakia, guarantor, belonging to the institution).
Edition RSC Advances, Cambridge, Royal Society of Chemistry, 2022, 2046-2069.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.900
RIV identification code RIV/00216224:14160/22:00126331
Organization unit Faculty of Pharmacy
Doi http://dx.doi.org/10.1039/d2ra00441k
UT WoS 000769020900001
Keywords in English NATURAL STILBENOIDSVITIS-VINIFERAIN-VITRORESVERATROLDEMETHYLATIONINHIBITORSARYL
Tags rivok, ÚChL, ÚPL
Tags International impact, Reviewed
Changed by Changed by: JUDr. Sabina Krejčiříková, učo 383857. Changed: 14/9/2022 08:37.
Abstract
An efficient and versatile synthesis of the naturally occurring C-prenylated stilbenoid methyl ethers and their synthetic analogues is presented. The synthesis represents a six step convergent process including an optimised C-prenylation method. Furthermore, during the demethylation process, six new dihydro-benzopyranyl derivatives were obtained and isolated.
Links
GF21-38204L, research and development projectName: Komplexy vybraných přechodných kovů s rostlinnými látkami s anti-NF-kappa B a pro-PPAR duální aktivitou
Investor: Czech Science Foundation, Partner Agency
MUNI/A/1682/2020, interní kód MUName: Návrh, syntéza a hodnocení derivátů skupin léčiv s inhibiční enzymatickou aktivitou
Investor: Masaryk University
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