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@article{193375,
author = {Dubový, Petr and Aldskogius, Hakan},
article_location = {Oxford},
article_number = {13},
keywords = {sensory corpuscles},
language = {eng},
issn = {0959-4965},
journal = {NeuroReport},
title = {Growth - associated protein (GAP-43) in terminal Schwann cells of rat Pacinian corpuscles},
volume = {7},
year = {1996}
}
TY - JOUR
ID - 193375
AU - Dubový, Petr - Aldskogius, Hakan
PY - 1996
TI - Growth - associated protein (GAP-43) in terminal Schwann cells of rat Pacinian corpuscles
JF - NeuroReport
VL - 7
IS - 13
SP - 2147
EP - 2147
PB - Oxford Press
SN - 09594965
KW - sensory corpuscles
N2 - GROWTH-ASSOCIATED protein (GAP-43) immunoreactivity was examined in Pacinian corpuscles of intact neonatal and adult rats as well as after denervation and reinnervation in adult rats. All immature Pacinian corpuscles were GAP-43 immunoreactive (GAP-43(+)) in their inner cores while only 46 +/- 5.6% of the mature corpuscles exhibited GAP-43(+) inner cores. The frequency of GAP-43(+) inner cores increased to 90 +/- 7.2% after their permanent denervation. The expression of GAP-43 in the inner cores was reduced by contact with regrowing axons, but 38 +/- 5.3% of Pacinian corpuscles retained GAP-43(+) in their inner cores following reinnervation. These results indicate that GAP-43 regulation is not confined only to axons but also involves some extra-axonal cues, and support a role for this protein in the process formation by terminal Schwann cells.
ER -
DUBOVÝ, Petr a Hakan ALDSKOGIUS. Growth - associated protein (GAP-43) in terminal Schwann cells of rat Pacinian corpuscles. Online. \textit{NeuroReport}. Oxford: Oxford Press, 1996, roč.~7, č.~13, s.~2147-2150. ISSN~0959-4965. [citováno 2024-04-24]
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