Detailed Information on Publication Record
1996
Alternative experimental approaches to reparation of nerve defects
HOUŠŤAVA, Ladislav and Petr DUBOVÝBasic information
Original name
Alternative experimental approaches to reparation of nerve defects
Name in Czech
Alternativní experimentální přístupy pro reparaci nervových defektů
Authors
HOUŠŤAVA, Ladislav (203 Czech Republic) and Petr DUBOVÝ (203 Czech Republic, guarantor)
Edition
Scripta Medica, Brno, Lékařská fakulta Masarykovy univerzity, 1996, 1211-3395
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/96:00028150
Organization unit
Faculty of Medicine
Keywords in English
animal experiment; animal tissue; behavior
Tags
International impact, Reviewed
Změněno: 19/6/2009 13:59, prof. RNDr. Petr Dubový, CSc.
V originále
This study evaluated the ability of acellular nerve and muscle grafts as well as knitwear nerve prosthesis covered by collagen 1 to enhance the recovery of function in injured rat sciatic nerves. Recovery of motor function was assessed by means of behavioural, electrophysiological and morphological methods. Proximal nerve slump stimulation as well as EMG measurements showed that both muscle and nerve acellular grafts as well as artificial wrapped nerve prosthesis were suitable conduits for regrowing axons that recovered functional connections with the skeletal muscles. Immunohistochemical and electron microscopical techniques confirmed the presence of myelinated axons in the nerve outgrowth and in the distal stumps. The artificial wrapped prosthesis seems to be promising for future consideration in nerve grafting.
In Czech
Byla studována schopnost acelulárních nervových a svalových graftů a pletených nervových protéz pro překonání přerušeného sedacího nervu laboratorního potkana.
Links
| IZ2605, research and development project |
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| IZ3126, research and development project |
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