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@article{201099,
author = {Houšťava, Ladislav and Dubový, Petr},
article_location = {Brno},
article_number = {69},
keywords = {animal experiment; animal tissue; behavior},
language = {eng},
issn = {1211-3395},
journal = {Scripta Medica},
title = {Alternative experimental approaches to reparation of nerve defects},
volume = {1996},
year = {1996}
}
TY - JOUR
ID - 201099
AU - Houšťava, Ladislav - Dubový, Petr
PY - 1996
TI - Alternative experimental approaches to reparation of nerve defects
JF - Scripta Medica
VL - 1996
IS - 69
SP - 241
EP - 241
PB - Lékařská fakulta Masarykovy univerzity
SN - 12113395
KW - animal experiment
KW - animal tissue
KW - behavior
N2 - This study evaluated the ability of acellular nerve and muscle grafts as well as knitwear nerve prosthesis covered by collagen 1 to enhance the recovery of function in injured rat sciatic nerves. Recovery of motor function was assessed by means of behavioural, electrophysiological and morphological methods. Proximal nerve slump stimulation as well as EMG measurements showed that both muscle and nerve acellular grafts as well as artificial wrapped nerve prosthesis were suitable conduits for regrowing axons that recovered functional connections with the skeletal muscles. Immunohistochemical and electron microscopical techniques confirmed the presence of myelinated axons in the nerve outgrowth and in the distal stumps. The artificial wrapped prosthesis seems to be promising for future consideration in nerve grafting.
ER -
HOUŠŤAVA, Ladislav and Petr DUBOVÝ. Alternative experimental approaches to reparation of nerve defects. \textit{Scripta Medica}. Brno: Lékařská fakulta Masarykovy univerzity, 1996, vol.~1996, No~69, p.~241-249. ISSN~1211-3395.
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