J 1999

Absence of thyroid hormones down regulates the expression of fast myosin heavy chain (MyHC) isoforms in regenerating soleus muscle isografted into fast extensor digitorum longus muscle

SOUKUP, Tomáš, I. ERŽEN, Isa JIRMANOVÁ, Gisela ZACHAŘOVÁ, Hana RAUCHOVÁ et. al.

Basic information

Original name

Absence of thyroid hormones down regulates the expression of fast myosin heavy chain (MyHC) isoforms in regenerating soleus muscle isografted into fast extensor digitorum longus muscle

Authors

SOUKUP, Tomáš (203 Czech Republic), I. ERŽEN (705 Slovenia), Isa JIRMANOVÁ (203 Czech Republic), Gisela ZACHAŘOVÁ (203 Czech Republic), Hana RAUCHOVÁ (203 Czech Republic) and Stanislav PAVELKA (203 Czech Republic, guarantor)

Edition

Physiological Research [IF=0.521(1998); SCI #cit.<2>], 1999, 0862-8408

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.521

RIV identification code

RIV/00216224:14310/99:00001208

Organization unit

Faculty of Science

Keywords in English

muscle; myosin; thyroid hormone

Tags

International impact, Reviewed
Změněno: 9/4/2010 19:08, doc. RNDr. Stanislav Pavelka, CSc.

Abstract

V originále

Slow soleus (SOL) muscles of 21- to 28-day-old inbred rats of the Lewis strain were grafted into the fast extensor digitorum longus (EDL) muscles in young adult euthyroid, hyperthyroid or hypothyroid inbred rats of the same strain. One to 12 months after the operation, rats were killed and muscle histochemical profiles and expression of myosin heavy chain (MyHC) isoforms were determined. From our results, it can be concluded that normal level of thyroid hormones is necessary for the expression of fast MyHC isoforms in the regenerating SOL muscle reinnervated by the fast EDL nerve.

Links

GA304/97/0516, research and development project
Name: Analýza vlivu myogenních a neurogenních faktorů na expresi specifického fenotypu intrafuzálních svalových vláken