PAVELKA, Stanislav, Arnošt BABICKÝ, Miloslav VOBECKÝ, Jaroslav LENER and Eva ŠVANDOVÁ. Bromide kinetics and distribution in the rat. I. Biokinetics of 82Br-bromide. Biological Trace Element Research [IF=0.786 (1999); SCI #cit.<7>]. 2000, vol. 76, 1,, p. 57-66. ISSN 0163-4984.
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Basic information
Original name Bromide kinetics and distribution in the rat. I. Biokinetics of 82Br-bromide.
Authors PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic), Miloslav VOBECKÝ (203 Czech Republic), Jaroslav LENER (203 Czech Republic) and Eva ŠVANDOVÁ (203 Czech Republic).
Edition Biological Trace Element Research [IF=0.786 (1999); SCI #cit.<7>], 2000, 0163-4984.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30105 Physiology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.786
RIV identification code RIV/00216224:14310/00:00003148
Organization unit Faculty of Science
Keywords in English Bromide;biokinetics;biological half-life;bromide space;radionuclide 82-Br; rat
Tags biokinetics, Biological half-life, bromide, bromide space, radionuclide 82-Br, rat
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Stanislav Pavelka, CSc., učo 313. Changed: 10/1/2009 15:26.
Abstract
Biological half-lives of bromine in 15 different organs and tissues of the rat, in addition to the whole-body half-life, were determined by measuring the radioactive concentration of 82Br-bromide in samples of tissues collected at the time intervals of 12-396 h from animals that continuously (up to 17 d) received 82Br-labeled bromide in their drinking water. In most of the studied tissues, the biological half-lives of bromine were shorter than in the whole body, in which it equalled 197.8+22.2 h. Significant correlation between the values of the steady-state concentration of bromide and of the biological half-life was found for most tissues.
Links
IAA7011813, research and development projectName: Vliv nadbytku bromu, jodového deficitu nebo jejich kombinace na metabolismus thyroidních hormonů ve tkáních
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