ARPÁŠ, Tomáš, Hana JELÍNKOVÁ, Štěpán HRABOVSKÝ, Martina ORŠULOVÁ, Zuzana VRZALOVÁ, Veronika NAVRKALOVÁ, Eva BRHELOVÁ, Lenka BRYJOVÁ, Alena BULIKOVÁ, Eva ONDROUŠKOVÁ, Markéta ŠEJNOHOVÁ, František FOLBER, Petra ŠEDOVÁ, Jiří MAYER, Šárka POSPÍŠILOVÁ, Marie JAROŠOVÁ and Michael DOUBEK. Very rare near-haploid acute lymphoblastic leukemia resistant to immunotherapy and CAR-T therapy in 19-year-old male patient. CLINICAL CASE REPORTS. ENGLAND: WILEY, 2022, vol. 10, No 3, p. 1-5. ISSN 2050-0904. Available from: https://dx.doi.org/10.1002/ccr3.5545.
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Basic information
Original name Very rare near-haploid acute lymphoblastic leukemia resistant to immunotherapy and CAR-T therapy in 19-year-old male patient
Authors ARPÁŠ, Tomáš (703 Slovakia, belonging to the institution), Hana JELÍNKOVÁ (203 Czech Republic), Štěpán HRABOVSKÝ (203 Czech Republic, belonging to the institution), Martina ORŠULOVÁ (703 Slovakia, belonging to the institution), Zuzana VRZALOVÁ (203 Czech Republic, belonging to the institution), Veronika NAVRKALOVÁ (203 Czech Republic, belonging to the institution), Eva BRHELOVÁ (203 Czech Republic, belonging to the institution), Lenka BRYJOVÁ (203 Czech Republic, belonging to the institution), Alena BULIKOVÁ (203 Czech Republic, belonging to the institution), Eva ONDROUŠKOVÁ (203 Czech Republic, belonging to the institution), Markéta ŠEJNOHOVÁ (203 Czech Republic, belonging to the institution), František FOLBER (203 Czech Republic, belonging to the institution), Petra ŠEDOVÁ (203 Czech Republic, belonging to the institution), Jiří MAYER (203 Czech Republic, belonging to the institution), Šárka POSPÍŠILOVÁ (203 Czech Republic, belonging to the institution), Marie JAROŠOVÁ (203 Czech Republic, belonging to the institution) and Michael DOUBEK (203 Czech Republic, guarantor, belonging to the institution).
Edition CLINICAL CASE REPORTS, ENGLAND, WILEY, 2022, 2050-0904.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30205 Hematology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 0.700
RIV identification code RIV/00216224:14110/22:00126446
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1002/ccr3.5545
UT WoS 000818987200123
Keywords in English acute lymphoblastic leukemia; blinatumomab; CAR-T therapy; inotuzumab ozogamicin; near-haploid
Tags 14110212, 14110323, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 31/3/2023 13:34.
Abstract
Near-haploid acute lymphoblastic leukemia is rare subgroup of the disease, which is very important due to very poor prognosis and resistance to treatment including novel monoclonal antibodies and CAR-T therapy.
Links
EF16_026/0008448, research and development projectName: Analýza českých genomů pro teranostiku
LM2018132, research and development projectName: Národní centrum lékařské genomiky (Acronym: NCLG)
Investor: Ministry of Education, Youth and Sports of the CR, National Center for Medical Genomics
LM2018133, research and development projectName: Český národní uzel Evropské infrastruktury pro translační medicínu (Acronym: EATRIS-ERIC-CZ)
Investor: Ministry of Education, Youth and Sports of the CR
MUNI/A/1595/2020, interní kód MUName: Nové přístupy ve výzkumu, diagnostice a terapii hematologických malignit VIII (Acronym: VýDiTeHeMa VIII)
Investor: Masaryk University
MUNI/11/SUP/22/2020, interní kód MUName: Zavedení technologie CRISPR/Cas9 pro funkční studie u familiárních hematopoetických onemocnění
Investor: Masaryk University
NU20-08-00137, research and development projectName: Vyhledávání a funkční testování variant genů predisponujících k familiárním onemocněním krvetvorby
Investor: Ministry of Health of the CR, Searching and functional testing of gene variants predisposing to familial haematopoietic disorders, Subprogram 1 - standard
TN01000013, research and development projectName: Personalizovaná medicína - diagnostika a terapie
Investor: Technology Agency of the Czech Republic, Personalized Medicine – Diagnostics and Therapy
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