Contrast-Enhanced Ultrasonography for Differential Diagnosis of
Benign and Malignant Thyroid Lesions: Single-Institutional
Prospective Study of Qualitati-ve and Quantitative CEUS
Characteristics.

J 2022

Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitati-ve and Quantitative CEUS Characteristics.

PETRÁŠOVÁ, Hana, Radka ŠLAISOVÁ, Tomáš ROHAN, Karel STARÝ, Jitka KYCLOVÁ et. al.

Basic information

Original name

Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitati-ve and Quantitative CEUS Characteristics.

Authors

PETRÁŠOVÁ, Hana (703 Slovakia, belonging to the institution), Radka ŠLAISOVÁ (203 Czech Republic, belonging to the institution), Tomáš ROHAN (203 Czech Republic, belonging to the institution), Karel STARÝ (203 Czech Republic), Jitka KYCLOVÁ (203 Czech Republic), Tomáš PAVLÍK (203 Czech Republic, belonging to the institution), Petra KOVALČÍKOVÁ (203 Czech Republic, belonging to the institution), Tomáš KAZDA (203 Czech Republic, guarantor, belonging to the institution) and Vlastimil VÁLEK (203 Czech Republic, belonging to the institution)

Edition

CONTRAST MEDIA & MOLECULAR IMAGING, LONDON, WILEY-HINDAWI, 2022, 1555-4309

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30224 Radiology, nuclear medicine and medical imaging

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.009 in 2021

RIV identification code

RIV/00216224:14110/22:00126462

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1155/2022/8229445

UT WoS

000822809100002

Keywords in English

FINE-NEEDLE-ASPIRATION; ULTRASOUND CEUS; NODULES; SOLITARY; CANCER; PREVALENCE; GUIDELINES; PROSTATE; RISK

Abstract

V originále

Objectives. To extend and revise the diagnostic value of contrast-enhanced ultrasonography (CEUS) for differentiation between malignant and benign thyroid nodules. Methods. This single-institution prospective study aims to compare CEUS qualitative and objective quantitative parameters in benign and malignant thyroid nodules. Consecutive cohort of 100 patients was examined by CEUS, 68 out of them were further analysed in detail. All included patients underwent cytological and/or histopathological verification of the diagnosis. Results. Fifty-five (81%) thyroid nodules were benign, and 13 (19%) were malignant. Ring enhancement pattern was strongly associated with a benign aetiology (positive predictive value 100%) and heterogeneous enhancement pattern with malignant aetiology (positive predictive value 72.7%). The shape of the TIC (time-intensity curve) was more often identical in the benign lesion (98.2%) than in malignant lesions (69.2%), p=0.004. Conclusions. This study indicates that CEUS enhancement patterns were significantly different in benign and malignant lesions. Ring enhancement was a very strong indicator of benign lesions, whereas heterogeneous enhancement was valuable to detect malignant lesions.

Citovat

PETRÁŠOVÁ, Hana, Radka ŠLAISOVÁ, Tomáš ROHAN, Karel STARÝ, Jitka KYCLOVÁ, Tomáš PAVLÍK, Petra KOVALČÍKOVÁ, Tomáš KAZDA and Vlastimil VÁLEK. Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitati-ve and Quantitative CEUS Characteristics. CONTRAST MEDIA & MOLECULAR IMAGING. LONDON: WILEY-HINDAWI, 2022, vol. 2022, April 2022, p. 1-10. ISSN 1555-4309. Available from: https://dx.doi.org/10.1155/2022/8229445.

@article{2212058,
   author = {Petrášová, Hana and Šlaisová, Radka and Rohan, Tomáš and Starý, Karel and Kyclová, Jitka and Pavlík, Tomáš and Kovalčíková, Petra and Kazda, Tomáš and Válek, Vlastimil},
   article_location = {LONDON},
   article_number = {April 2022},
   doi = {http://dx.doi.org/10.1155/2022/8229445},
   keywords = {FINE-NEEDLE-ASPIRATION; ULTRASOUND CEUS; NODULES; SOLITARY; CANCER; PREVALENCE; GUIDELINES; PROSTATE; RISK},
   language = {eng},
   issn = {1555-4309},
   journal = {CONTRAST MEDIA & MOLECULAR IMAGING},
   title = {Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitati-ve and Quantitative CEUS Characteristics.},
   url = {https://www.hindawi.com/journals/cmmi/2022/8229445/},
   volume = {2022},
   year = {2022}
}

TY  - JOUR
ID  - 2212058
AU  - Petrášová, Hana - Šlaisová, Radka - Rohan, Tomáš - Starý, Karel - Kyclová, Jitka - Pavlík, Tomáš - Kovalčíková, Petra - Kazda, Tomáš - Válek, Vlastimil
PY  - 2022
TI  - Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitati-ve and Quantitative CEUS Characteristics.
JF  - CONTRAST MEDIA & MOLECULAR IMAGING
VL  - 2022
IS  - April 2022
SP  - 1-10
EP  - 1-10
PB  - WILEY-HINDAWI
SN  - 15554309
KW  - FINE-NEEDLE-ASPIRATION
KW  - ULTRASOUND CEUS
KW  - NODULES
KW  - SOLITARY
KW  - CANCER
KW  - PREVALENCE
KW  - GUIDELINES
KW  - PROSTATE
KW  - RISK
UR  - https://www.hindawi.com/journals/cmmi/2022/8229445/
N2  - Objectives. To extend and revise the diagnostic value of contrast-enhanced ultrasonography (CEUS) for differentiation between malignant and benign thyroid nodules. Methods. This single-institution prospective study aims to compare CEUS qualitative and objective quantitative parameters in benign and malignant thyroid nodules. Consecutive cohort of 100 patients was examined by CEUS, 68 out of them were further analysed in detail. All included patients underwent cytological and/or histopathological verification of the diagnosis. Results. Fifty-five (81%) thyroid nodules were benign, and 13 (19%) were malignant. Ring enhancement pattern was strongly associated with a benign aetiology (positive predictive value 100%) and heterogeneous enhancement pattern with malignant aetiology (positive predictive value 72.7%). The shape of the TIC (time-intensity curve) was more often identical in the benign lesion (98.2%) than in malignant lesions (69.2%), p=0.004. Conclusions. This study indicates that CEUS enhancement patterns were significantly different in benign and malignant lesions. Ring enhancement was a very strong indicator of benign lesions, whereas heterogeneous enhancement was valuable to detect malignant lesions.
ER  -

PETRÁŠOVÁ, Hana, Radka ŠLAISOVÁ, Tomáš ROHAN, Karel STARÝ, Jitka KYCLOVÁ, Tomáš PAVLÍK, Petra KOVALČÍKOVÁ, Tomáš KAZDA and Vlastimil VÁLEK. Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitati-ve and Quantitative CEUS Characteristics. \textit{CONTRAST MEDIA \&{} MOLECULAR IMAGING}. LONDON: WILEY-HINDAWI, 2022, vol.~2022, April 2022, p.~1-10. ISSN~1555-4309. Available from: https://dx.doi.org/10.1155/2022/8229445.

Detailed Information on Publication Record