Monofunctionalized Fluorinated Bambusurils and Their Conjugates
for Anion Transport and Extraction

J 2022

Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction

DE SIMONE, Nicola Alessandro, Matúš CHVOJKA, Jana LAPEŠOVÁ, Luis MARTÍNEZ-CRESPO, Petr SLÁVIK et. al.

Basic information

Original name

Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction

Authors

DE SIMONE, Nicola Alessandro (380 Italy, belonging to the institution), Matúš CHVOJKA (703 Slovakia, belonging to the institution), Jana LAPEŠOVÁ (203 Czech Republic, belonging to the institution), Luis MARTÍNEZ-CRESPO, Petr SLÁVIK (203 Czech Republic, belonging to the institution), Jan SOKOLOV (203 Czech Republic, belonging to the institution), Stephen J. BUTLER, Hennie VALKENIER and Vladimír ŠINDELÁŘ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Organic Chemistry, American Chemical Society, 2022, 0022-3263

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10400 1.4 Chemical sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.600

RIV identification code

RIV/00216224:14310/22:00126597

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1021/acs.joc.2c00870

UT WoS

000886435300001

Keywords in English

Anions; Assays; Extraction; Macrocycles; Reaction products

Abstract

V originále

Bambusurils are macrocyclic molecules that are known for their high binding affinity and selectivity toward anions. Here, we present the preparation of two bambusurils bearing fluorinated substituents and one carboxylic function. These monofunctionalized bambusurils were conjugated with crown ether and cholesterol units. The resulting conjugates were successfully tested in liquid–liquid extraction of inorganic salts and chloride/bicarbonate transport across lipid bilayers.

Links

EF17_043/0009632, research and development project

Name: CETOCOEN Excellence

GA20-13922S, research and development project

Name: Monofunkcializované bambusurily a jejich supramolekulární vlastnosti

Investor: Czech Science Foundation

LM2018121, research and development project

Name: Výzkumná infrastruktura RECETOX (Acronym: RECETOX RI)

Investor: Ministry of Education, Youth and Sports of the CR, RECETOX RI

LM2018127, research and development project

Name: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)

Investor: Ministry of Education, Youth and Sports of the CR

857560, interní kód MU
(CEP code: EF17_043/0009632)

Name: CETOCOEN Excellence (Acronym: CETOCOEN Excellence)

Investor: European Union, Spreading excellence and widening participation

Citovat

DE SIMONE, Nicola Alessandro, Matúš CHVOJKA, Jana LAPEŠOVÁ, Luis MARTÍNEZ-CRESPO, Petr SLÁVIK, Jan SOKOLOV, Stephen J. BUTLER, Hennie VALKENIER and Vladimír ŠINDELÁŘ. Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction. Journal of Organic Chemistry. American Chemical Society, 2022, vol. 87, No 15, p. 9829-9838. ISSN 0022-3263. Available from: https://dx.doi.org/10.1021/acs.joc.2c00870.

@article{2215758,
   author = {De Simone, Nicola Alessandro and Chvojka, Matúš and Lapešová, Jana and MartínezandCrespo, Luis and Slávik, Petr and Sokolov, Jan and Butler, Stephen J. and Valkenier, Hennie and Šindelář, Vladimír},
   article_number = {15},
   doi = {http://dx.doi.org/10.1021/acs.joc.2c00870},
   keywords = {Anions; Assays; Extraction; Macrocycles; Reaction products},
   language = {eng},
   issn = {0022-3263},
   journal = {Journal of Organic Chemistry},
   title = {Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction},
   url = {https://doi.org/10.1021/acs.joc.2c00870},
   volume = {87},
   year = {2022}
}

TY  - JOUR
ID  - 2215758
AU  - De Simone, Nicola Alessandro - Chvojka, Matúš - Lapešová, Jana - Martínez-Crespo, Luis - Slávik, Petr - Sokolov, Jan - Butler, Stephen J. - Valkenier, Hennie - Šindelář, Vladimír
PY  - 2022
TI  - Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction
JF  - Journal of Organic Chemistry
VL  - 87
IS  - 15
SP  - 9829-9838
EP  - 9829-9838
PB  - American Chemical Society
SN  - 00223263
KW  - Anions
KW  - Assays
KW  - Extraction
KW  - Macrocycles
KW  - Reaction products
UR  - https://doi.org/10.1021/acs.joc.2c00870
N2  - Bambusurils are macrocyclic molecules that are known for their high binding affinity and selectivity toward anions. Here, we present the preparation of two bambusurils bearing fluorinated substituents and one carboxylic function. These monofunctionalized bambusurils were conjugated with crown ether and cholesterol units. The resulting conjugates were successfully tested in liquid–liquid extraction of inorganic salts and chloride/bicarbonate transport across lipid bilayers.
ER  -

DE SIMONE, Nicola Alessandro, Matúš CHVOJKA, Jana LAPEŠOVÁ, Luis MARTÍNEZ-CRESPO, Petr SLÁVIK, Jan SOKOLOV, Stephen J. BUTLER, Hennie VALKENIER and Vladimír ŠINDELÁŘ. Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction. \textit{Journal of Organic Chemistry}. American Chemical Society, 2022, vol.~87, No~15, p.~9829-9838. ISSN~0022-3263. Available from: https://dx.doi.org/10.1021/acs.joc.2c00870.

Detailed Information on Publication Record