If we detect changes in the chemical composition (mostly zonal development or the occurrence of different mineral phases) via electron microprobe, it is also possible to assume the existence of structural changes visible in the Raman spectra in form of a band shifts or bandwidth variations. Presence of such changes may relate to substitution mechanisms and distribution of different impurities may be confirmed by LA-ICP-MS 2D imaging (especially sub-ppm elements previously not detected on EPMA). Interrelationships between structure and chemical composition can then be sought in interesting correlations between these techniques.