Surgery due to Inflammatory Bowel Disease During Pregnancy: Mothers and Offspring Outcomes From an ECCO Confer Multicentre Case Series [Scar Study]

CHAPARRO, Maria, Lumír KUNOVSKÝ, Mariam AGUAS, Moran LIVNE, Pauline RIVIERE, Ariella Bar-Gil SHITRIT, Par MYRELID, Maite ARROYO, Acosta Manuel BARREIRO-DE, Michelle BAUTISTA, Livia BIANCONE, Irit Avni BIRON, Trine BOYSEN, Daniel CARPIO, Beatriz CASTRO, Gabriele DRAGONI, Pierre ELLUL, Stefan D HOLUBAR, Angel de Jorge MIGUEL, Eduardo LEO, Noemi MANCENIDO, Annick MOENS, Tamas MOLNAR, Ramirez de la Piscina PATRICIA, Petr RICANEK, Ladislava SEBKOVA, Laura SEMPERE, Niels TEICH, Javier P GISBERT and Mette JULSGAARD. Surgery due to Inflammatory Bowel Disease During Pregnancy: Mothers and Offspring Outcomes From an ECCO Confer Multicentre Case Series [Scar Study]. JOURNAL OF CROHNS & COLITIS. OXFORD: OXFORD UNIV PRESS, vol. 16, No 9, p. 1428-1435. ISSN 1873-9946. doi:10.1093/ecco-jcc/jjac050. 2022.

Basic information

• Original name: Surgery due to Inflammatory Bowel Disease During Pregnancy: Mothers and Offspring Outcomes From an ECCO Confer Multicentre Case Series [Scar Study]
• Authors: CHAPARRO, Maria (guarantor), Lumír KUNOVSKÝ (203 Czech Republic, belonging to the institution), Mariam AGUAS, Moran LIVNE, Pauline RIVIERE, Ariella Bar-Gil SHITRIT, Par MYRELID, Maite ARROYO, Acosta Manuel BARREIRO-DE, Michelle BAUTISTA, Livia BIANCONE, Irit Avni BIRON, Trine BOYSEN, Daniel CARPIO, Beatriz CASTRO, Gabriele DRAGONI, Pierre ELLUL, Stefan D HOLUBAR, Angel de Jorge MIGUEL, Eduardo LEO, Noemi MANCENIDO, Annick MOENS, Tamas MOLNAR, Ramirez de la Piscina PATRICIA, Petr RICANEK, Ladislava SEBKOVA, Laura SEMPERE, Niels TEICH, Javier P GISBERT and Mette JULSGAARD.
• Edition: JOURNAL OF CROHNS & COLITIS, OXFORD, OXFORD UNIV PRESS, 2022, 1873-9946.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30219 Gastroenterology and hepatology
• Country of publisher: United Kingdom of Great Britain and Northern Ireland
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 8.000
• RIV identification code: RIV/00216224:14110/22:00126644
• Organization unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1093/ecco-jcc/jjac050
• UT WoS: 000796675700001
• Keywords in English: Inflammatory bowel disease; Crohn's disease; ulcerative colitis; pregnancy; gestation; surgery
• Tags: 14110223, rivok
• Tags: International impact, Reviewed

Abstract

Aims i] To evaluate the evolution of pregnancies and offspring after inflammatory bowel disease [IBD] surgery during pregnancy; and ii] to describe the indications, the surgical techniques, and the frequency of caesarean section concomitant with surgery. Methods Patients operated on due to IBD during pregnancy after 1998 were included. Participating clinicians were asked to review their databases to identify cases. Data on patients' demographics, IBD characteristics, medical treatments, IBD activity, pregnancy outcomes, surgery, delivery, and foetal and maternal outcomes, were recorded. Results In all, 44 IBD patients were included, of whom 75% had Crohn's disease; 18% of the surgeries were performed in the first trimester, 55% in the second, and 27% in the third trimester. One patient had complications during surgery, and 27% had postsurgical complications. No patient died. Of deliveries, 70% were carried out by caesarean section. There were 40 newborns alive. There were four miscarriages/stillbirths [one in the first, two in the second, and one in the third trimester]; two occurred during surgery, and another two occurred 2 weeks after surgery; 14% of the surgeries during the second trimester and 64% of those in the third trimester ended up with a simultaneous caesarean section or vaginal delivery. Of the 40 newborns, 61% were premature and 47% had low birth weight; 42% of newborns needed hospitalisation [25% in the intensive care unit]. Conclusions IBD surgery during pregnancy remains an extremely serious situation. Therefore, surgical management should be performed in a multidisciplinary team, involving gastroenterologists, colorectal surgeons, obstetricians, and neonatal specialists.