k 2022

TARGETING METALLOENZYMES WITH NEWLY DESIGNED INHIBITORS FOR POTENTIAL THERAPEUTIC INTERVENTION

ONUŠČÁKOVÁ, Magdaléna, Hana PÍŽOVÁ, Miroslav KEMKA, Vladimír GARAJ, Pavel BOBÁĽ et. al.

Basic information

Original name

TARGETING METALLOENZYMES WITH NEWLY DESIGNED INHIBITORS FOR POTENTIAL THERAPEUTIC INTERVENTION

Authors

ONUŠČÁKOVÁ, Magdaléna (703 Slovakia, guarantor, belonging to the institution), Hana PÍŽOVÁ (203 Czech Republic, belonging to the institution), Miroslav KEMKA (703 Slovakia), Vladimír GARAJ (703 Slovakia) and Pavel BOBÁĽ (703 Slovakia, belonging to the institution)

Edition

SAL 2022 Brno, 2022

Other information

Language

English

Type of outcome

Prezentace na konferencích

Field of Study

30107 Medicinal chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14160/22:00126654

Organization unit

Faculty of Pharmacy

Keywords in English

metalloproteins_molecular docking_p-coumaric acid
Změněno: 13/9/2022 14:21, PharmDr. Magdaléna Onuščáková

Abstract

V originále

Almost half of all enzymes must cooperate with metal ions to function. Most metalloproteins play a crucial role in metabolically essential processes. They also significantly impact the progression of various human diseases, including cancer, heart disease, and HIV/AIDS. Due to this reason, they are an attractive medical target for the treatment of a wide range of human disorders.

Links

MUNI/IGA/1339/2021, interní kód MU
Name: Design, synthesis and evaluation of potential metalloenzymes inhibitors (Acronym: DSEPMI)
Investor: Masaryk University