2022
Omics-based approach to study honey bee (Apis mellifera) response to parasitic mite Varroa sp. and associated pathogens
DOBEŠ, Pavel; Martin KUNC; Jana HURYCHOVÁ; Sara ELIÁŠ; Pavel HYRŠL et. al.Basic information
Original name
Omics-based approach to study honey bee (Apis mellifera) response to parasitic mite Varroa sp. and associated pathogens
Name in Czech
Omics-based approach to study honey bee (Apis mellifera) response to parasitic mite Varroa sp. and associated pathogens
Authors
DOBEŠ, Pavel (203 Czech Republic, guarantor, belonging to the institution); Martin KUNC (203 Czech Republic, belonging to the institution); Jana HURYCHOVÁ (203 Czech Republic, belonging to the institution); Sara ELIÁŠ (276 Germany, belonging to the institution) and Pavel HYRŠL (203 Czech Republic, belonging to the institution)
Edition
Frontiers in Physiology and Disease, 2022
Other information
Language
English
Type of outcome
Requested lectures
Field of Study
10608 Biochemistry and molecular biology
Country of publisher
Czech Republic
Confidentiality degree
is not subject to a state or trade secret
RIV identification code
RIV/00216224:14310/22:00129442
Organization unit
Faculty of Science
Keywords (in Czech)
včela medonosná; Varroa destructor; parazitismus; transkriptomika; proteomika; metabolomika; imunitní odpověď; přezimování
Keywords in English
honey bee; Varroa destructor; parasitism; transcriptomics; proteomics; metabolomics; immune response; overwintering
Tags
International impact, Reviewed
Changed: 19/9/2022 01:29, Mgr. Pavel Dobeš, Ph.D.
V originále
Honey bees (Apis mellifera L.) are the most important managed pollinators worldwide, and according to the estimates, about two-thirds of crops used in human food production are dependent on pollination. A long history of domestication and international transport of A. mellifera has resulted in a cosmopolitan distribution of the bees, but unfortunately, also its pathogens and parasites, which are considered to be one of the main factors behind honey bee losses. Therefore, the global decline of the honey bee population poses a significant social, economic, and scientific concern. Despite years of intensive research, the complex mechanisms of Varroa-honey bee interaction are still not untangled. Therefore, we employed a unique combination of transcriptomic, proteomic, metabolomic, and functional analyses to reveal new details about the effect of Varroa mites and naturally associated factors, including viruses, on honey bees. We focused on differences between Varroa-parasitised and unparasitised ten-day-old worker bees collected before overwintering from the same set of colonies reared without anti-mite treatment. Significant changes were observed at all organismal levels in immunity, oxidative stress response, olfactory recognition and other specific processes. Moreover, the supplementary comparison to honey bees collected from colonies with standard anti-Varroa treatment provides insights into the effect of a pyrethroid flumethrin. Recent findings of omics analyses help reveal new details of honey bee response to parasitic mites and suggest new ways to control diseases of this beneficial insect. Our work is supported by the Ministry of Agriculture of the Czech Republic grant NAZV no. QK1910286; SFI Research Infrastructure Call 2012 (12/RI/2346 (3)) and Projects of Large Research, Development and Innovations Infrastructures "e-Infrastruktura CZ" (e-INFRA LM2018140).
In Czech
Honey bees (Apis mellifera L.) are the most important managed pollinators worldwide, and according to the estimates, about two-thirds of crops used in human food production are dependent on pollination. A long history of domestication and international transport of A. mellifera has resulted in a cosmopolitan distribution of the bees, but unfortunately, also its pathogens and parasites, which are considered to be one of the main factors behind honey bee losses. Therefore, the global decline of the honey bee population poses a significant social, economic, and scientific concern. Despite years of intensive research, the complex mechanisms of Varroa-honey bee interaction are still not untangled. Therefore, we employed a unique combination of transcriptomic, proteomic, metabolomic, and functional analyses to reveal new details about the effect of Varroa mites and naturally associated factors, including viruses, on honey bees. We focused on differences between Varroa-parasitised and unparasitised ten-day-old worker bees collected before overwintering from the same set of colonies reared without anti-mite treatment. Significant changes were observed at all organismal levels in immunity, oxidative stress response, olfactory recognition and other specific processes. Moreover, the supplementary comparison to honey bees collected from colonies with standard anti-Varroa treatment provides insights into the effect of a pyrethroid flumethrin. Recent findings of omics analyses help reveal new details of honey bee response to parasitic mites and suggest new ways to control diseases of this beneficial insect. Our work is supported by the Ministry of Agriculture of the Czech Republic grant NAZV no. QK1910286; SFI Research Infrastructure Call 2012 (12/RI/2346 (3)) and Projects of Large Research, Development and Innovations Infrastructures "e-Infrastruktura CZ" (e-INFRA LM2018140).
Links
| QK1910286, research and development project |
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