k 2022

Assessment of rate of major complications in transarterial chemoembolization using degradable starch microspheres versus permanent embolization particles in patients with hepatocellular carcinoma

STRAKA, Matej, Tomáš ROHAN, Peter MATKULČÍK, Jakub HUSTÝ, Tomáš ANDRAŠINA et. al.

Basic information

Original name

Assessment of rate of major complications in transarterial chemoembolization using degradable starch microspheres versus permanent embolization particles in patients with hepatocellular carcinoma

Authors

Edition

CIRSE 2022, 2022

Other information

Language

English

Type of outcome

Prezentace na konferencích

Field of Study

30224 Radiology, nuclear medicine and medical imaging

Country of publisher

Spain

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Organization unit

Faculty of Medicine

DOI

UT WoS

000852601000002

Keywords in English

hepatocellular carcinoma; HCC; transarterial chemoembolisation; TACE; complications; degradable particles; DSM TACE
Změněno: 3/4/2023 10:33, Mgr. Tereza Miškechová

Abstract

V originále

Purpose: To analyze whether transarterial chemoembolization (TACE) using degradable starch microspheres (DSM-TACE) or permanent embolizing particles (DEB-TACE) cause significant difference in rate of major periprocedural complications in patients with hepatocellular carcinoma (HCC). Materials and methods: Prospective assessment of major periprocedural complications in 226 TACE procedures between 2018-2021 in 57 consecutive patients with HCC was performed. Study group consists of 110 DSM-TACE procedures, the control group consists of 116 procedures using permanent embolizing particles. Major complications were followed up to 30 days after each TACE (contrast-enhanced CT, laboratory parameters, clinical status). Our data underwent statical analyses (chi-squared test). Results: There was significant difference in complication per procedure in the study and the control group (3% vs 14% p=0,006). Complications after TACE included severe postembolization syndrome (n=11), liver ischemia caused by reflux of permanent particles (n=4), liver abscess (n=2), cholangitis (n=2), allergic reaction (n=1). Conclusion: Patients with HCC treated with TACE using permanent embolization particles have significantly higher frequency of major postprocedural complication compared to patients with HCC treated with TACE using degradable particles.

Links

MUNI/A/1388/2021, interní kód MU
Name: Význam radiologických intervencí a pokročilých zobrazovacích metod v diagnostice a léčbě pacientů s maligním onemocněním
Investor: Masaryk University