STRAKA, Matej, Tomáš ROHAN, Peter MATKULČÍK, Jakub HUSTÝ and Tomáš ANDRAŠINA. Assessment of rate of major complications in transarterial chemoembolization using degradable starch microspheres versus permanent embolization particles in patients with hepatocellular carcinoma. In CIRSE 2022. 2022. Available from: https://dx.doi.org/10.1007/s00270-022-03246-4.
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Original name Assessment of rate of major complications in transarterial chemoembolization using degradable starch microspheres versus permanent embolization particles in patients with hepatocellular carcinoma
Authors STRAKA, Matej, Tomáš ROHAN, Peter MATKULČÍK, Jakub HUSTÝ and Tomáš ANDRAŠINA.
Edition CIRSE 2022, 2022.
Other information
Original language English
Type of outcome Presentations at conferences
Field of Study 30224 Radiology, nuclear medicine and medical imaging
Country of publisher Spain
Confidentiality degree is not subject to a state or trade secret
WWW URL
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s00270-022-03246-4
UT WoS 000852601000002
Keywords in English hepatocellular carcinoma; HCC; transarterial chemoembolisation; TACE; complications; degradable particles; DSM TACE
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 3/4/2023 10:33.
Abstract
Purpose: To analyze whether transarterial chemoembolization (TACE) using degradable starch microspheres (DSM-TACE) or permanent embolizing particles (DEB-TACE) cause significant difference in rate of major periprocedural complications in patients with hepatocellular carcinoma (HCC). Materials and methods: Prospective assessment of major periprocedural complications in 226 TACE procedures between 2018-2021 in 57 consecutive patients with HCC was performed. Study group consists of 110 DSM-TACE procedures, the control group consists of 116 procedures using permanent embolizing particles. Major complications were followed up to 30 days after each TACE (contrast-enhanced CT, laboratory parameters, clinical status). Our data underwent statical analyses (chi-squared test). Results: There was significant difference in complication per procedure in the study and the control group (3% vs 14% p=0,006). Complications after TACE included severe postembolization syndrome (n=11), liver ischemia caused by reflux of permanent particles (n=4), liver abscess (n=2), cholangitis (n=2), allergic reaction (n=1). Conclusion: Patients with HCC treated with TACE using permanent embolization particles have significantly higher frequency of major postprocedural complication compared to patients with HCC treated with TACE using degradable particles.
Links
MUNI/A/1388/2021, interní kód MUName: Význam radiologických intervencí a pokročilých zobrazovacích metod v diagnostice a léčbě pacientů s maligním onemocněním
Investor: Masaryk University
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