Comparison of the Effect on Vessel Density and RNFL between
Carteolol and Latanoprost

J 2022

Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost

NUTTEROVÁ, Elena; Martin FUS; Libuse BARTOSOVA; Iva KLIMESOVA; Jan LESTAK et. al.

Základní údaje

Originální název

Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost

Autoři

NUTTEROVÁ, Elena; Martin FUS; Libuse BARTOSOVA; Iva KLIMESOVA a Jan LESTAK

Vydání

Journal of Clinical Medicine, Basel, MDPI, 2022, 2077-0383

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.900

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.3390/jcm11144159

UT WoS

000833373300001

Klíčová slova anglicky

hypertensive glaucoma; OCTA; vessel density; RNFL; treatment with carteolol and latanoprost

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 27. 9. 2022 14:24, Mgr. Tereza Miškechová

Anotace

V originále

The aim of the study was to compare the treatment of hypertensive glaucoma (HTG) in the early stages with carteolol and latanoprost by assessing the change in vessel density (VD) and retinal nerve fibre layer (RNFL). Methods: The first group with diagnosed HTG consisted of 46 eyes treated with carteolol; the second group consisted of 52 eyes treated with latanoprost. The following examinations were evaluated in all patients: intraocular pressure (IOP), retinal nerve fibre layer (RNFL), vessel density (VD) and visual field examination (glaucoma fast threshold test). The results were compared before treatment and 3 months after treatment. Results: There was no difference in the overall visual field defect (OD) between groups before treatment. After treatment, there was a decrease in IOP in both groups (carteolol-treated group had a mean decrease of 5.8 mmHg and latanoprost-treated eyes had a mean decrease of 7 mmHg). This difference was not statistically significant (p = 0.133). No similar difference was observed for RNFL (p = 0.161). In contrast, the change in the VD parameter was statistically significant between groups (p < 0.05), with a greater difference observed in the carteolol-treated group of eyes. Carteolol had a better effect on the VD.

Citovat

NUTTEROVÁ, Elena; Martin FUS; Libuse BARTOSOVA; Iva KLIMESOVA a Jan LESTAK. Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost. Journal of Clinical Medicine. Basel: MDPI, 2022, roč. 11, č. 14, s. 1-7. ISSN 2077-0383. Dostupné z: https://dx.doi.org/10.3390/jcm11144159.

@article{2220979,
   author = {Nutterová, Elena and Fus, Martin and Bartosova, Libuse and Klimesova, Iva and Lestak, Jan},
   article_location = {Basel},
   article_number = {14},
   doi = {http://dx.doi.org/10.3390/jcm11144159},
   keywords = {hypertensive glaucoma; OCTA; vessel density; RNFL; treatment with carteolol and latanoprost},
   language = {eng},
   issn = {2077-0383},
   journal = {Journal of Clinical Medicine},
   note = {Bez afiliace k MU.},
   title = {Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost},
   url = {https://www.mdpi.com/2077-0383/11/14/4159},
   volume = {11},
   year = {2022}
}

TY  - JOUR
ID  - 2220979
AU  - Nutterová, Elena - Fus, Martin - Bartosova, Libuse - Klimesova, Iva - Lestak, Jan
PY  - 2022
TI  - Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost
JF  - Journal of Clinical Medicine
VL  - 11
IS  - 14
SP  - 1-7
EP  - 1-7
PB  - MDPI
SN  - 20770383
N1  - Bez afiliace k MU.
KW  - hypertensive glaucoma
KW  - OCTA
KW  - vessel density
KW  - RNFL
KW  - treatment with carteolol and latanoprost
UR  - https://www.mdpi.com/2077-0383/11/14/4159
N2  - The aim of the study was to compare the treatment of hypertensive glaucoma (HTG) in the early stages with carteolol and latanoprost by assessing the change in vessel density (VD) and retinal nerve fibre layer (RNFL). Methods: The first group with diagnosed HTG consisted of 46 eyes treated with carteolol; the second group consisted of 52 eyes treated with latanoprost. The following examinations were evaluated in all patients: intraocular pressure (IOP), retinal nerve fibre layer (RNFL), vessel density (VD) and visual field examination (glaucoma fast threshold test). The results were compared before treatment and 3 months after treatment. Results: There was no difference in the overall visual field defect (OD) between groups before treatment. After treatment, there was a decrease in IOP in both groups (carteolol-treated group had a mean decrease of 5.8 mmHg and latanoprost-treated eyes had a mean decrease of 7 mmHg). This difference was not statistically significant (p = 0.133). No similar difference was observed for RNFL (p = 0.161). In contrast, the change in the VD parameter was statistically significant between groups (p < 0.05), with a greater difference observed in the carteolol-treated group of eyes. Carteolol had a better effect on the VD.
ER  -

NUTTEROVÁ, Elena; Martin FUS; Libuse BARTOSOVA; Iva KLIMESOVA a Jan LESTAK. Comparison of the Effect on Vessel Density and RNFL between Carteolol and Latanoprost. \textit{Journal of Clinical Medicine}. Basel: MDPI, 2022, roč.~11, č.~14, s.~1-7. ISSN~2077-0383. Dostupné z: https://dx.doi.org/10.3390/jcm11144159.

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