| DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, Lenka SOUČKOVÁ, Jan CHRASTINA, Jan CHLÁDEK, Radka ŠTĚPÁNOVÁ and Milan BRÁZDIL. Prediction of Vagal Nerve Stimulation Efficacy in Drug-Resistant Epilepsy (PRECISE): Prospective Study for Pre-implantation Prediction/Study Design. FRONTIERS IN NEUROLOGY. LAUSANNE: FRONTIERS MEDIA SA, 2022, vol. 13, March 2022, p. 1-9. ISSN 1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2022.839163. |
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@article{2222185,
author = {Doležalová, Irena and Koriťáková, Eva and Součková, Lenka and Chrastina, Jan and Chládek, Jan and Štěpánová, Radka and Brázdil, Milan},
article_location = {LAUSANNE},
article_number = {March 2022},
doi = {http://dx.doi.org/10.3389/fneur.2022.839163},
keywords = {drug-resistant epilepsy; efficacy prediction; statistical model; study design; vagal nerve stimulation.},
language = {eng},
issn = {1664-2295},
journal = {FRONTIERS IN NEUROLOGY},
title = {Prediction of Vagal Nerve Stimulation Efficacy in Drug-Resistant Epilepsy (PRECISE): Prospective Study for Pre-implantation Prediction/Study Design},
url = {https://pubmed.ncbi.nlm.nih.gov/35386419/},
volume = {13},
year = {2022}
}
TY - JOUR
ID - 2222185
AU - Doležalová, Irena - Koriťáková, Eva - Součková, Lenka - Chrastina, Jan - Chládek, Jan - Štěpánová, Radka - Brázdil, Milan
PY - 2022
TI - Prediction of Vagal Nerve Stimulation Efficacy in Drug-Resistant Epilepsy (PRECISE): Prospective Study for Pre-implantation Prediction/Study Design
JF - FRONTIERS IN NEUROLOGY
VL - 13
IS - March 2022
SP - 1-9
EP - 1-9
PB - FRONTIERS MEDIA SA
SN - 16642295
KW - drug-resistant epilepsy
KW - efficacy prediction
KW - statistical model
KW - study design
KW - vagal nerve stimulation.
UR - https://pubmed.ncbi.nlm.nih.gov/35386419/
N2 - Vagal nerve stimulation (VNS) can be indicated in patients with drug-resistant epilepsy, who are not eligible for resective epilepsy surgery. In VNS therapy, the responder rate (i.e., percentage of subjects experiencing ≥50% seizure reduction) is ~50%. At the moment, there is no widely-accepted possibility to predict VNS efficacy in a particular patient based on pre-implantation data, which can lead to unnecessary surgery and improper allocation of financial resources. The principal aim of PRediction of vagal nerve stimulation EfficaCy In drug-reSistant Epilepsy (PRECISE) study is to verify the predictability of VNS efficacy by analysis of pre-implantation routine electroencephalogram (EEG).
ER -
DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, Lenka SOUČKOVÁ, Jan CHRASTINA, Jan CHLÁDEK, Radka ŠTĚPÁNOVÁ and Milan BRÁZDIL. Prediction of Vagal Nerve Stimulation Efficacy in Drug-Resistant Epilepsy (PRECISE): Prospective Study for Pre-implantation Prediction/Study Design. \textit{FRONTIERS IN NEUROLOGY}. LAUSANNE: FRONTIERS MEDIA SA, 2022, vol.~13, March 2022, p.~1-9. ISSN~1664-2295. Available from: https://dx.doi.org/10.3389/fneur.2022.839163.
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