Guidelines an adoption of Muscle-invasive and Metastatic Bladder Cancer at the national level in the Czech Republic

BÚŘILOVÁ, Petra, Jiří BÚŘIL, Andrea GABRIELOVÁ, Miloslav KLUGAR and Marek BABJUK. Guidelines an adoption of Muscle-invasive and Metastatic Bladder Cancer at the national level in the Czech Republic. In GIN 2022, Toronto. 2022.

Basic information

• Original name: Guidelines an adoption of Muscle-invasive and Metastatic Bladder Cancer at the national level in the Czech Republic
• Authors: BÚŘILOVÁ, Petra, Jiří BÚŘIL, Andrea GABRIELOVÁ, Miloslav KLUGAR and Marek BABJUK.
• Edition: GIN 2022, Toronto, 2022.

Other information

• Original language: English
• Type of outcome: Presentations at conferences
• Field of Study: 30217 Urology and nephrology
• Country of publisher: Canada
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Organization unit: Faculty of Medicine
• Keywords in English: Bladder cancer; clinical practice guideline; GRADE

Abstract

Background Significant advances in diagnostics and innovative treatment options in urology-oncology are changing the patient care environment and the way healthcare is delivered. The systematic search and rigorous evaluation by AGREE II tool identified feasible guideline from the European Urological Society (AEU). The guidelines for muscle-invasive and metastatic bladder cancer offer new care delivery opportunities in the Czech Republic. Objective Transformation of recommendations from international guidelines for setting policies and unification of care provided at the national level in the Czech Republic. Methods Adaptation of 2019 AEU and innovative transformation of the visual style of recommendation and its Certainty of Evidence (CoE) and Strength of Recommendation (SoR) following the GRADE approach was utilized. Results The selected guideline for adaptation assessed by the AGREEII tool received the highest score in six domains and used the modified GRADE methodology. Recommendations were assessed and contextualized by the broad expert panel on health system needs in the Czech Republic. Discussion The methodology board assessed in detail the development of each recommendation that was adopted. Based on the available information, the evidence was visually transformed according to the GRADE methodology. Recommendations were also supplemented with commentary by the experts in the case of treatments that are not currently covered by general health insurance, and recommendation toward public health was developed for such treatments.