J 2022

Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.

MIHALČIN, Matúš, Libuše HUSOVÁ, Petra VAŠÍČKOVÁ, Marcel BENA, Petr HUSA et. al.

Basic information

Original name

Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.

Authors

MIHALČIN, Matúš (703 Slovakia, guarantor, belonging to the institution), Libuše HUSOVÁ (203 Czech Republic), Petra VAŠÍČKOVÁ (203 Czech Republic), Marcel BENA and Petr HUSA (203 Czech Republic, belonging to the institution)

Edition

Archives of Medical Science, Poland, Termedia Publishing House, 2022, 1734-1922

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30218 General and internal medicine

Country of publisher

Poland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.800

RIV identification code

RIV/00216224:14110/22:00126979

Organization unit

Faculty of Medicine

DOI

UT WoS

000869187900028

Keywords in English

therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis

Tags

Tags

International impact, Reviewed
Změněno: 7/11/2022 08:12, Mgr. Tereza Miškechová

Abstract

V originále

Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Material and methods: The retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.