p 2022

Laser ablation imaging in bioapplications

KUCHYNKA, Michaela, Peter SCHEER, Jana HLOŽKOVÁ, Radka OPATŘILOVÁ, Tereza PADRTOVÁ et. al.

Basic information

Original name

Laser ablation imaging in bioapplications

Name in Czech

Zobrazování pomocí laserové ablace v bioaplikacích

Authors

KUCHYNKA, Michaela (203 Czech Republic, belonging to the institution), Peter SCHEER (203 Czech Republic, belonging to the institution), Jana HLOŽKOVÁ (203 Czech Republic, belonging to the institution), Radka OPATŘILOVÁ (203 Czech Republic, belonging to the institution), Tereza PADRTOVÁ (203 Czech Republic, belonging to the institution), Viktor KANICKÝ (203 Czech Republic, belonging to the institution), Marcela VLČNOVSKÁ (203 Czech Republic, belonging to the institution) and Tomáš VACULOVIČ (203 Czech Republic, belonging to the institution)

Edition

2022 Winter Conference on Plasma Spectrochemistry, 2022

Other information

Language

English

Type of outcome

Vyžádané přednášky

Field of Study

10406 Analytical chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14310/22:00129197

Organization unit

Faculty of Science

Keywords in English

bioimaging; laser ablation; protein determination; element distribution

Tags

International impact
Změněno: 21/10/2022 11:00, Mgr. Michaela Kuchynka, Ph.D.

Abstract

V originále

In the last decades, increased interest in imaging of elements/metals/proteins distribution, mainly in pharmaceutical, biomedicine research, or life science with application to specific problems/diseases. The main emphasis of this paper is to demonstrate LA-ICP-MS as a unique method that opens new opportunities to achieve simultaneous determination of elements and proteins. These proteins are imaged by utilizing antibody labelling by nanoparticles. Therefore, it can be obtained comprehensive metalloproteomics information about diseases, in this case, cancer or brain stroke.

Links

GA20-02203S, research and development project
Name: Analýza tkáňové odpovědi na inhalaci nanočástic kovů a mechanismus jejich čištění
Investor: Czech Science Foundation
MUNI/R/1568/2020, interní kód MU
Name: Study the effectiveness of anticancer drugs (Acronym: STEAD)
Investor: Masaryk University, CAREER RESTART