KUCHYNKA, Michaela, Michal MASAŘÍK, Marcela VLČNOVSKÁ, Viktor KANICKÝ and Tomáš VACULOVIČ. Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry. 2019.
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Basic information
Original name Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
Name (in English) Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
Authors KUCHYNKA, Michaela, Michal MASAŘÍK, Marcela VLČNOVSKÁ, Viktor KANICKÝ and Tomáš VACULOVIČ.
Edition 2019.
Other information
Type of outcome Presentations at conferences
Confidentiality degree is not subject to a state or trade secret
WWW URL URL
Keywords in English Nanoparticles; Bioimaging; LA, ICP, MS; Immunochemistry
Tags PATFYZ, ÚCh
Tags International impact
Changed by Changed by: Mgr. Michaela Kuchynka, Ph.D., učo 358018. Changed: 21/10/2022 13:20.
Abstract
Laser ablation with inductively coupled plasma is still more used in life science as biology and biomedicine and the utilization of metals and proteins determination simultaneously is also growing up. We have developed a new strategy of antibody labeling by nanoparticles which are composed of thousands of atoms and thus increase the sensitivity enormously and decrease the limit of detection (tens of picograms). The ability of simultaneous imaging proteins such as p53 and elements and their distribution in biological tissue (especially tumour) is presented in this work.
Links
GA17-12774S, research and development projectName: Využití vícenásobného značení pomocí kovových nanočástic pro bio-zobrazování
Investor: Czech Science Foundation
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 31/7/2024 00:17