Detailed Information on Publication Record
2019
Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
KUCHYNKA, Michaela, Michal MASAŘÍK, Marcela VLČNOVSKÁ, Viktor KANICKÝ, Tomáš VACULOVIČ et. al.Basic information
Original name
Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
Name (in English)
Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
Authors
Edition
2019
Other information
Type of outcome
Prezentace na konferencích
Confidentiality degree
není předmětem státního či obchodního tajemství
Keywords in English
Nanoparticles; Bioimaging; LA, ICP, MS; Immunochemistry
Tags
International impact
Změněno: 21/10/2022 13:20, Mgr. Michaela Kuchynka, Ph.D.
Abstract
V originále
Laser ablation with inductively coupled plasma is still more used in life science as biology and biomedicine and the utilization of metals and proteins determination simultaneously is also growing up. We have developed a new strategy of antibody labeling by nanoparticles which are composed of thousands of atoms and thus increase the sensitivity enormously and decrease the limit of detection (tens of picograms). The ability of simultaneous imaging proteins such as p53 and elements and their distribution in biological tissue (especially tumour) is presented in this work.
Links
| GA17-12774S, research and development project |
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| LQ1601, research and development project |
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