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@inproceedings{223052, author = {Michálek, Jaroslav and Šmarda, Jan}, address = {Praha}, booktitle = {Cells}, keywords = {acute myeloid leukemia}, language = {eng}, location = {Praha}, isbn = {80-7232-069-6}, pages = {96-96}, publisher = {Czechoslovak Biological Society}, title = {The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia}, year = {1999} }
TY - JOUR ID - 223052 AU - Michálek, Jaroslav - Šmarda, Jan PY - 1999 TI - The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia PB - Czechoslovak Biological Society CY - Praha SN - 8072320696 KW - acute myeloid leukemia N2 - Eighty percent of children with AML show clonal chromosomal aberrations on cytogenetic examination. The most frequent aberrations rexognised in AML are t(8;21), t(15;17), inv(16) and 11q23. These aberrations comprise 10-45% of all AML cases in choldren. Recently, the molecular genetic examination of these specific changes is available with the sensitivity of finding one leukemic cell bearing the translocation in between 1 million of normal cells. ER -
MICHÁLEK, Jaroslav and Jan ŠMARDA. The advantage of PCR method in monitoring of specific chromosomal aberration in children with acute myeloid leukaemia. In \textit{Cells}. Praha: Czechoslovak Biological Society, 1999, p.~96. ISBN~80-7232-069-6.
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