Importance of experimental evaluation of structural parameters
for constitutive modelling of aorta

J 2023

Importance of experimental evaluation of structural parameters for constitutive modelling of aorta

FISCHER, Jiří, Michaela TURČANOVÁ, Vojtěch MAN, Markéta HERMANOVÁ, Zdeněk BEDNAŘÍK et. al.

Basic information

Original name

Importance of experimental evaluation of structural parameters for constitutive modelling of aorta

Authors

FISCHER, Jiří (203 Czech Republic, guarantor), Michaela TURČANOVÁ (203 Czech Republic), Vojtěch MAN (203 Czech Republic), Markéta HERMANOVÁ (203 Czech Republic, belonging to the institution), Zdeněk BEDNAŘÍK (203 Czech Republic, belonging to the institution) and Jiří BURŠA (203 Czech Republic)

Edition

Journal of the Mechanical Behavior of Biomedical Materials, AMSTERDAM, ELSEVIER, 2023, 1751-6161

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30109 Pathology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.900 in 2022

RIV identification code

RIV/00216224:14110/23:00134025

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.jmbbm.2022.105615

UT WoS

000899579700003

Keywords in English

Soft tissue; Collagen; Fibre direction; Polarized light microscopy; Histogram; Constitutive modelling

Abstract

V originále

The study compares stresses and strains in the aortic wall derived using different constitutive models for various stress-strain conditions. Structure-based constitutive models with two fibre families with (GOH) and without (HGO) dispersion of collagen fibres are compared. The constitutive models were fitted to data from equibiaxial tension tests of two separated layers of the porcine aortic wall. The initial fit was evaluated with unrestricted parameters and subsequently, the mean angles of the fibre families and the angular dispersion were fixed to the values obtained from histology. Surprisingly, none of the tested models was capable to provide a good quality fit with histologically obtained structural parameters. Fitting the HGO model to experimental data resulted in two fibre families under angles close to ±45°, while the GOH model resulted in a nearly isotropic fibre distribution. These results indicate that both of these models suffer from the absence of isotropic strain stiffening. After having modified both models with corresponding additional members based on the Yeoh model of matrix, we obtained a perfect fit to the measured data while keeping the structural histology-based parameters. Finally, significant differences in compliance and resulting stresses and strains between different models are shown by means of simulations of uniaxial tension test, equibiaxial tension tests and inflation of the aorta.

Links

GA21-21935S, research and development project

Name: Výpočtové modelování pulzačního proudění v poddajných trubicích s aplikací na tandemovou stenózu karotidy

Investor: Czech Science Foundation

Citovat

FISCHER, Jiří, Michaela TURČANOVÁ, Vojtěch MAN, Markéta HERMANOVÁ, Zdeněk BEDNAŘÍK and Jiří BURŠA. Importance of experimental evaluation of structural parameters for constitutive modelling of aorta. Journal of the Mechanical Behavior of Biomedical Materials. AMSTERDAM: ELSEVIER, 2023, vol. 138, February 2023, p. 1-8. ISSN 1751-6161. Available from: https://dx.doi.org/10.1016/j.jmbbm.2022.105615.

@article{2239427,
   author = {Fischer, Jiří and Turčanová, Michaela and Man, Vojtěch and Hermanová, Markéta and Bednařík, Zdeněk and Burša, Jiří},
   article_location = {AMSTERDAM},
   article_number = {February 2023},
   doi = {http://dx.doi.org/10.1016/j.jmbbm.2022.105615},
   keywords = {Soft tissue; Collagen; Fibre direction; Polarized light microscopy; Histogram; Constitutive modelling},
   language = {eng},
   issn = {1751-6161},
   journal = {Journal of the Mechanical Behavior of Biomedical Materials},
   title = {Importance of experimental evaluation of structural parameters for constitutive modelling of aorta},
   url = {https://www.sciencedirect.com/science/article/pii/S1751616122005203?via%3Dihub},
   volume = {138},
   year = {2023}
}

TY  - JOUR
ID  - 2239427
AU  - Fischer, Jiří - Turčanová, Michaela - Man, Vojtěch - Hermanová, Markéta - Bednařík, Zdeněk - Burša, Jiří
PY  - 2023
TI  - Importance of experimental evaluation of structural parameters for constitutive modelling of aorta
JF  - Journal of the Mechanical Behavior of Biomedical Materials
VL  - 138
IS  - February 2023
SP  - 1-8
EP  - 1-8
PB  - ELSEVIER
SN  - 17516161
KW  - Soft tissue
KW  - Collagen
KW  - Fibre direction
KW  - Polarized light microscopy
KW  - Histogram
KW  - Constitutive modelling
UR  - https://www.sciencedirect.com/science/article/pii/S1751616122005203?via%3Dihub
N2  - The study compares stresses and strains in the aortic wall derived using different constitutive models for various stress-strain conditions. Structure-based constitutive models with two fibre families with (GOH) and without (HGO) dispersion of collagen fibres are compared. The constitutive models were fitted to data from equibiaxial tension tests of two separated layers of the porcine aortic wall. The initial fit was evaluated with unrestricted parameters and subsequently, the mean angles of the fibre families and the angular dispersion were fixed to the values obtained from histology. Surprisingly, none of the tested models was capable to provide a good quality fit with histologically obtained structural parameters. Fitting the HGO model to experimental data resulted in two fibre families under angles close to ±45°, while the GOH model resulted in a nearly isotropic fibre distribution. These results indicate that both of these models suffer from the absence of isotropic strain stiffening. After having modified both models with corresponding additional members based on the Yeoh model of matrix, we obtained a perfect fit to the measured data while keeping the structural histology-based parameters. Finally, significant differences in compliance and resulting stresses and strains between different models are shown by means of simulations of uniaxial tension test, equibiaxial tension tests and inflation of the aorta.
ER  -

FISCHER, Jiří, Michaela TURČANOVÁ, Vojtěch MAN, Markéta HERMANOVÁ, Zdeněk BEDNAŘÍK and Jiří BURŠA. Importance of experimental evaluation of structural parameters for constitutive modelling of aorta. \textit{Journal of the Mechanical Behavior of Biomedical Materials}. AMSTERDAM: ELSEVIER, 2023, vol.~138, February 2023, p.~1-8. ISSN~1751-6161. Available from: https://dx.doi.org/10.1016/j.jmbbm.2022.105615.

Detailed Information on Publication Record