Detailed Information on Publication Record
2022
ヌクレアーゼの阻害剤としての置換プロパンアミド
PARUCH, Kamil, Benoit Jean-Pierre CARBAIN, Štěpán HAVEL, Vít VŠIANSKÝ, Fedor NIKULENKOV et. al.Basic information
Original name
ヌクレアーゼの阻害剤としての置換プロパンアミド
Name (in English)
Substituted propanamides as inhibitors of nucleases
Authors
PARUCH, Kamil (203 Czech Republic, guarantor, belonging to the institution), Benoit Jean-Pierre CARBAIN (250 France, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Vít VŠIANSKÝ (203 Czech Republic, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution) and Lumír KREJČÍ (203 Czech Republic, belonging to the institution)
Edition
Number: JP7148999, Publisher: Japan Patent office, Place of publication: Kasumigaseki, Chiyoda-ku Tokyo, Owner's name: Masarykova univerzita, 2022
Other information
Language
Japanese
Type of outcome
Patent
Field of Study
10401 Organic chemistry
Country of publisher
Japan
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
RIV identification code
RIV/00216224:14310/22:00127610
Organization unit
Faculty of Science
Keywords in English
DNA; propanamide; nuclease
Změněno: 22/3/2023 11:20, Mgr. Marie Šípková, DiS.
V originále
本発明は、構造式(1)によって表される化合物を提供する: 【化1】 式中、 R1、R2、R3、R4、R5、R6は、特許請求の範囲で定義されている通りである。当該化合物は、ヌクレアーゼの阻害剤であり、特に、増殖性疾患、神経変性疾患、および他のゲノム不安定性関連疾患の治療方法および/または予防方法において、有用である。
In English
The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Links
EF16_025/0007381, research and development project |
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LM2018130, research and development project |
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