PARUCH, Kamil, Benoit Jean-Pierre CARBAIN, Štěpán HAVEL, Vít VŠIANSKÝ, Fedor NIKULENKOV and Lumír KREJČÍ. Substituted propanamides as inhibitors of nucleases. 2022.
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Basic information
Original name Substituted propanamides as inhibitors of nucleases
Authors PARUCH, Kamil (203 Czech Republic, guarantor, belonging to the institution), Benoit Jean-Pierre CARBAIN (250 France, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Vít VŠIANSKÝ (203 Czech Republic, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution) and Lumír KREJČÍ (203 Czech Republic, belonging to the institution).
Edition Number: US11453663, Publisher: United States Patent and Trademark Office, Place of publication: Alexandria, Virginia, Owner's name: Masarykova univerzita, 2022.
Other information
Original language English
Type of outcome Patent
Field of Study 10401 Organic chemistry
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14310/22:00127612
Organization unit Faculty of Science
Keywords in English DNA; propanamide; nuclease
Tags rivok
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 22/3/2023 13:17.
Abstract
Compounds represented by the structural formula (1) where R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Links
EF16_025/0007381, research and development projectName: Preklinická progrese nových organických sloučenin s cílenou biologickou aktivitou
LM2018130, research and development projectName: Národní infrastruktura chemické biologie (Acronym: CZ-­OPENSCREEN)
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 19/7/2024 09:36