The majority of foreign works even today state that despite all existing recommendations for acute treatment Postoperative pain Approximately 30-40% of patients experience severe pain after surgery. More extensive we do not have epidemiological data from the Czech Republic available. However, it can be rightly assumed that the situation here no better than in the mentioned countries. If we start from the data that over 800,000 are filed with us every year of general and regional anesthesia for surgical procedures, it is easy to calculate that 250-300 thousand of operated patients has significant post-operative pain every year, which can last for several days.