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@article{2243088,
author = {Antalová, Natália and Klučka, Jozef and Říhová, Markéta and Poláčková, Silvie and Pokorná, Andrea and Štourač, Petr},
article_location = {BASEL, SWITZERLAND},
article_number = {10},
doi = {http://dx.doi.org/10.3390/children9101540},
keywords = {ventilator-associated pneumonia; children; pediatric; intensive care; prevention},
language = {eng},
issn = {2227-9067},
journal = {Children-Basel},
title = {Ventilator-Associated Pneumonia Prevention in Pediatric Patients: Narrative Review},
url = {https://www.mdpi.com/2227-9067/9/10/1540},
volume = {9},
year = {2022}
}
TY - JOUR
ID - 2243088
AU - Antalová, Natália - Klučka, Jozef - Říhová, Markéta - Poláčková, Silvie - Pokorná, Andrea - Štourač, Petr
PY - 2022
TI - Ventilator-Associated Pneumonia Prevention in Pediatric Patients: Narrative Review
JF - Children-Basel
VL - 9
IS - 10
SP - 1-7
EP - 1-7
PB - MDPI
SN - 22279067
KW - ventilator-associated pneumonia
KW - children
KW - pediatric
KW - intensive care
KW - prevention
UR - https://www.mdpi.com/2227-9067/9/10/1540
N2 - Ventilator-associated pneumonia (VAP), one of the most common healthcare-associated infections in intensive care settings, is associated with significant morbidity and mortality. VAP is diagnosed in >10% of patients on mechanical ventilation, incidence rising with number of ventilator days. In recent decades, the pathophysiology of VAP, VAP risk factors and treatment have been extensively studied. In critically ill pediatric patients, mechanical issues such as insufficient tightness of the ventilator circuit (mainly due to historically based preference of uncuffed tubes) and excessive humidity in the circuit are both significant risk factors of VAP development. Protocol-based approaches to critically ill patients on mechanical ventilation, closed suctioning, upper body position, enteral feeding and selective gastric acid suppression medication have a beneficial effect on VAP incidence. In recent decades, cuffed tubes applied to the whole spectrum of critically ill pediatric patients (except neonates <2700 g of weight), together with cuff-oriented nursing care including proper cuff-pressure (<20 cm H2O) management and the use of specialized tracheal tubes with subglottic suction ports combined with close infraglottic tracheal suctioning, have been implemented. The aim of this review was to summarize the current evidence-based knowledge about the pathophysiology, risk factors, diagnosis, treatment and prevention of VAP in clinically oriented settings.
ER -
ANTALOVÁ, Natália, Jozef KLUČKA, Markéta ŘÍHOVÁ, Silvie POLÁČKOVÁ, Andrea POKORNÁ and Petr ŠTOURAČ. Ventilator-Associated Pneumonia Prevention in Pediatric Patients: Narrative Review. \textit{Children-Basel}. BASEL, SWITZERLAND: MDPI, 2022, vol.~9, No~10, p.~1-7. ISSN~2227-9067. Available from: https://dx.doi.org/10.3390/children9101540.
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