Case report: radiation-induced lumbosacral plexopathy - a very
late complication of radiotherapy for cervical cancer

J 2022

Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer

KRKOŠKA, Peter, Tomáš KAZDA, Daniela VLAŽNÁ and Blanka ADAMOVÁ

Basic information

Original name

Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer

Authors

KRKOŠKA, Peter (703 Slovakia, guarantor, belonging to the institution), Tomáš KAZDA (203 Czech Republic, belonging to the institution), Daniela VLAŽNÁ (703 Slovakia, belonging to the institution) and Blanka ADAMOVÁ (203 Czech Republic, belonging to the institution)

Edition

BMC Neurology, London, Biomed Central Ltd. 2022, 1471-2377

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.600

RIV identification code

RIV/00216224:14110/22:00127742

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1186/s12883-022-03013-5

UT WoS

000898457900002

Keywords in English

Radiation-induced lumbosacral plexopathy; Lumbosacral plexus; Cervical cancer; Radiotherapy; Case report

Abstract

V originále

Background: Lumbosacral plexopathy caused by radiotherapy is a rare but severe consequence of cancer treatment. This condition often leads to varying degrees of sensory and motor impairment. Neurological complications, which are typically permanent, manifest a long period after irradiation. Case presentation: We describe a case of progressive lower extremity weakness and sensory impairment in a woman who had been effectively treated with radiotherapy for cervical cancer with development 36 years after irradiation. The electrophysiological assessment revealed a subacute bilateral axonal lesion of the lumbosacral plexus. None of the clinical manifestations, serology, cerebrospinal fluid or imaging data discovered an explanation other than radiation-induced lumbosacral plexopathy (RILP). Conclusions: This case demonstrates that RILP may emerge more than 30 years after the radiotherapy.

Links

MUNI/A/1144/2021, interní kód MU

Name: Diagnostika a patofyziologie neuropatické bolesti a dalších symptomů a komorbidit neurologických onemocnění

Investor: Masaryk University

MUNI/IGA/1162/2021, interní kód MU

Name: The effect of regular exercise on the clinical status and paraspinal muscles in patients with chronic low back pain

Investor: Masaryk University

Citovat

KRKOŠKA, Peter, Tomáš KAZDA, Daniela VLAŽNÁ and Blanka ADAMOVÁ. Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer. BMC Neurology. London: Biomed Central Ltd., 2022, vol. 22, No 1, p. 1-6. ISSN 1471-2377. Available from: https://dx.doi.org/10.1186/s12883-022-03013-5.

@article{2243957,
   author = {Krkoška, Peter and Kazda, Tomáš and Vlažná, Daniela and Adamová, Blanka},
   article_location = {London},
   article_number = {1},
   doi = {http://dx.doi.org/10.1186/s12883-022-03013-5},
   keywords = {Radiation-induced lumbosacral plexopathy; Lumbosacral plexus; Cervical cancer; Radiotherapy; Case report},
   language = {eng},
   issn = {1471-2377},
   journal = {BMC Neurology},
   title = {Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer},
   url = {https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-022-03013-5},
   volume = {22},
   year = {2022}
}

TY  - JOUR
ID  - 2243957
AU  - Krkoška, Peter - Kazda, Tomáš - Vlažná, Daniela - Adamová, Blanka
PY  - 2022
TI  - Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer
JF  - BMC Neurology
VL  - 22
IS  - 1
SP  - 1-6
EP  - 1-6
PB  - Biomed Central Ltd.
SN  - 14712377
KW  - Radiation-induced lumbosacral plexopathy
KW  - Lumbosacral plexus
KW  - Cervical cancer
KW  - Radiotherapy
KW  - Case report
UR  - https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-022-03013-5
N2  - Background: Lumbosacral plexopathy caused by radiotherapy is a rare but severe consequence of cancer treatment. This condition often leads to varying degrees of sensory and motor impairment. Neurological complications, which are typically permanent, manifest a long period after irradiation. Case presentation: We describe a case of progressive lower extremity weakness and sensory impairment in a woman who had been effectively treated with radiotherapy for cervical cancer with development 36 years after irradiation. The electrophysiological assessment revealed a subacute bilateral axonal lesion of the lumbosacral plexus. None of the clinical manifestations, serology, cerebrospinal fluid or imaging data discovered an explanation other than radiation-induced lumbosacral plexopathy (RILP). Conclusions: This case demonstrates that RILP may emerge more than 30 years after the radiotherapy.
ER  -

KRKOŠKA, Peter, Tomáš KAZDA, Daniela VLAŽNÁ and Blanka ADAMOVÁ. Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer. \textit{BMC Neurology}. London: Biomed Central Ltd., 2022, vol.~22, No~1, p.~1-6. ISSN~1471-2377. Available from: https://dx.doi.org/10.1186/s12883-022-03013-5.

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