k 2022

Anti-inflammatory potential of selected phenolic compounds isolated from Morus alba

NYKODÝMOVÁ, Daniela, Michaela MÁTLOVÁ, Marie ČULENOVÁ and Jakub TREML

Basic information

Original name

Anti-inflammatory potential of selected phenolic compounds isolated from Morus alba

Authors

NYKODÝMOVÁ, Daniela (203 Czech Republic, belonging to the institution), Michaela MÁTLOVÁ (203 Czech Republic, belonging to the institution), Marie ČULENOVÁ (203 Czech Republic, belonging to the institution) and Jakub TREML (203 Czech Republic, belonging to the institution)

Edition

Synthesis and Analysis of Drugs (SAL) 2022, 2022

Other information

Language

English

Type of outcome

Prezentace na konferencích

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14160/22:00127865

Organization unit

Faculty of Pharmacy

ISBN

978-80-280-0110-0

Keywords in English

NF-κB; Morus alba; flavonoids; anti-inflammatory

Tags

Změněno: 11/1/2023 11:32, Mgr. Bc. Daniela Nykodýmová

Abstract

V originále

A series of phenolic compounds isolated from Morus alba (mulberrofuran A and B, mulberroside C, kuwanon C, U, and H) was selected for anti-inflammatory activity verification based on the traditional usage of the source. The study determined test compounds' inhibitory effect on the NF-κB/AP-1 cellular pathway using a QUANTI-Blue™ assay. Mulberrofuran B has demonstrated the highest inhibitory effect among the test compounds, comparable to the positive control results (prednisolone).

Links

MUNI/A/1654/2020, interní kód MU
Name: Testování biologické aktivity vybraných přírodních látek in vitro
Investor: Masaryk University