PETZOLD, Axel (guarantor), Clare L FRASER, Mathias ABEGG, Raed ALROUGHANI, Daniah ALSHOWAEIR, Regina ALVARENGA, Cecile ANDRIS, Nasrin ASGARI, Yael BARNETT, Roberto BATTISTELLA, Raed BEHBEHANI, Thomas BERGER, Mukharram M BIKBOV, Damien BIOTTI, Valerie BIOUSSE, Antonella BOSCHI, Milan BRÁZDIL (203 Czech Republic, belonging to the institution), Andrei BREZHNEV, Peter A CALABRESI, Monique CORDONNIER, Fiona COSTELLO, Franz M CRUZ, Leonardo Provetti CUNHA, Smail DAOUDI, Romain DESCHAMPS, de Seze JEROME, Ricarda DIEM, Masoud ETEMADIFAR, Jose FLORES-RIVERA, Pedro FONSECA, Jette FREDERIKSEN, Elliot FROHMAN, Teresa FROHMAN, Caroline Froment TILIKETE, Kazuo FUJIHARA, Alberto GALVEZ, Riadh GOUIDER, Fernando GRACIA, Nikolaos GRIGORIADIS, Jose M GUAJARDO, Mario HABEK, Marko HAWLINA, Elena H MARTINEZ-LAPISCINA, Juzar HOOKER, Jyh Yung HOR, William HOWLETT, Yumin HUANG-LINK, Zhannat IDRISSOVA, Zsolt ILLES, Jasna JANCIC, Panitha JINDAHRA, Dimitrios KARUSSIS, Emilia KERTY, Ho Jin KIM, Wolf LAGREZE, Letizia LEOCANI, Netta LEVIN, Petra LISKOVA, Yaou LIU, Youssoufa MAIGA, Romain MARIGNIER, Chris MCGUIGAN, Dalia MEIRA, Harold MERLE, Mario L R MONTEIRO, Anand MOODLEY, Frederico MOURA, Silvia MUNOZ, Sharik MUSTAFA, Ichiro NAKASHIMA, Susana NOVAL, Carlos OEHNINGER, Olufunmilola OGUN, Afekhide OMOTI, Lekha PANDIT, Friedemann PAUL, Gema REBOLLEDA, Stephen REDDEL, Konrad REJDAK, Robert REJDAK, Alfonso J RODRIGUEZ-MORALES, Marie-Benedicte ROUGIER, Maria Jose SA, Bernardo SANCHEZ-DALMAU, Deanna SAYLOR, Ismail SHATRIAH, Aksel SIVA, Hadas STIEBEL-KALISH, Gabriella SZATMARY, Linh TA, Silvia TENEMBAUM, Huy TRAN, Yevgen TRUFANOV, van Pesch VINCENT, An-Guor WANG, Mike P WATTJES, Ernest WILLOUGHBY, Magd ZAKARIA, Jasmin ZVORNICANIN, Laura BALCER and Gordon T PLANT
There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can facilitate the timely treatment of individuals with multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein antibody-associated disease. Epidemiological data show that, cumulatively, optic neuritis is most frequently caused by many conditions other than multiple sclerosis. Worldwide, the cause and management of optic neuritis varies with geographical location, treatment availability, and ethnic background. We have developed diagnostic criteria for optic neuritis and a classification of optic neuritis subgroups. Our diagnostic criteria are based on clinical features that permit a diagnosis of possible optic neuritis; further paraclinical tests, utilising brain, orbital, and retinal imaging, together with antibody and other protein biomarker data, can lead to a diagnosis of definite optic neuritis. Paraclinical tests can also be applied retrospectively on stored samples and historical brain or retinal scans, which will be useful for future validation studies. Our criteria have the potential to reduce the risk of misdiagnosis, provide information on optic neuritis disease course that can guide future treatment trial design, and enable physicians to judge the likelihood of a need for long-term pharmacological management, which might differ according to optic neuritis subgroups.
PETZOLD, Axel, Clare L FRASER, Mathias ABEGG, Raed ALROUGHANI, Daniah ALSHOWAEIR, Regina ALVARENGA, Cecile ANDRIS, Nasrin ASGARI, Yael BARNETT, Roberto BATTISTELLA, Raed BEHBEHANI, Thomas BERGER, Mukharram M BIKBOV, Damien BIOTTI, Valerie BIOUSSE, Antonella BOSCHI, Milan BRÁZDIL, Andrei BREZHNEV, Peter A CALABRESI, Monique CORDONNIER, Fiona COSTELLO, Franz M CRUZ, Leonardo Provetti CUNHA, Smail DAOUDI, Romain DESCHAMPS, de Seze JEROME, Ricarda DIEM, Masoud ETEMADIFAR, Jose FLORES-RIVERA, Pedro FONSECA, Jette FREDERIKSEN, Elliot FROHMAN, Teresa FROHMAN, Caroline Froment TILIKETE, Kazuo FUJIHARA, Alberto GALVEZ, Riadh GOUIDER, Fernando GRACIA, Nikolaos GRIGORIADIS, Jose M GUAJARDO, Mario HABEK, Marko HAWLINA, Elena H MARTINEZ-LAPISCINA, Juzar HOOKER, Jyh Yung HOR, William HOWLETT, Yumin HUANG-LINK, Zhannat IDRISSOVA, Zsolt ILLES, Jasna JANCIC, Panitha JINDAHRA, Dimitrios KARUSSIS, Emilia KERTY, Ho Jin KIM, Wolf LAGREZE, Letizia LEOCANI, Netta LEVIN, Petra LISKOVA, Yaou LIU, Youssoufa MAIGA, Romain MARIGNIER, Chris MCGUIGAN, Dalia MEIRA, Harold MERLE, Mario L R MONTEIRO, Anand MOODLEY, Frederico MOURA, Silvia MUNOZ, Sharik MUSTAFA, Ichiro NAKASHIMA, Susana NOVAL, Carlos OEHNINGER, Olufunmilola OGUN, Afekhide OMOTI, Lekha PANDIT, Friedemann PAUL, Gema REBOLLEDA, Stephen REDDEL, Konrad REJDAK, Robert REJDAK, Alfonso J RODRIGUEZ-MORALES, Marie-Benedicte ROUGIER, Maria Jose SA, Bernardo SANCHEZ-DALMAU, Deanna SAYLOR, Ismail SHATRIAH, Aksel SIVA, Hadas STIEBEL-KALISH, Gabriella SZATMARY, Linh TA, Silvia TENEMBAUM, Huy TRAN, Yevgen TRUFANOV, van Pesch VINCENT, An-Guor WANG, Mike P WATTJES, Ernest WILLOUGHBY, Magd ZAKARIA, Jasmin ZVORNICANIN, Laura BALCER and Gordon T PLANT. Diagnosis and classification of optic neuritis. Lancet Neurology. London, UK: Elsevier, 2022, vol. 21, No 12, p. 1120-1134. ISSN 1474-4422. Available from: https://dx.doi.org/10.1016/S1474-4422(22)00200-9.
@article{2247589, author = {Petzold, Axel and Fraser, Clare L and Abegg, Mathias and Alroughani, Raed and Alshowaeir, Daniah and Alvarenga, Regina and Andris, Cecile and Asgari, Nasrin and Barnett, Yael and Battistella, Roberto and Behbehani, Raed and Berger, Thomas and Bikbov, Mukharram M and Biotti, Damien and Biousse, Valerie and Boschi, Antonella and Brázdil, Milan and Brezhnev, Andrei and Calabresi, Peter A and Cordonnier, Monique and Costello, Fiona and Cruz, Franz M and Cunha, Leonardo Provetti and Daoudi, Smail and Deschamps, Romain and Jerome, de Seze and Diem, Ricarda and Etemadifar, Masoud and FloresandRivera, Jose and Fonseca, Pedro and Frederiksen, Jette and Frohman, Elliot and Frohman, Teresa and Tilikete, Caroline Froment and Fujihara, Kazuo and Galvez, Alberto and Gouider, Riadh and Gracia, Fernando and Grigoriadis, Nikolaos and Guajardo, Jose M and Habek, Mario and Hawlina, Marko and MartinezandLapiscina, Elena H and Hooker, Juzar and Hor, Jyh Yung and Howlett, William and HuangandLink, Yumin and Idrissova, Zhannat and Illes, Zsolt and Jancic, Jasna and Jindahra, Panitha and Karussis, Dimitrios and Kerty, Emilia and Kim, Ho Jin and Lagreze, Wolf and Leocani, Letizia and Levin, Netta and Liskova, Petra and Liu, Yaou and Maiga, Youssoufa and Marignier, Romain and McGuigan, Chris and Meira, Dalia and Merle, Harold and Monteiro, Mario L R and Moodley, Anand and Moura, Frederico and Munoz, Silvia and Mustafa, Sharik and Nakashima, Ichiro and Noval, Susana and Oehninger, Carlos and Ogun, Olufunmilola and Omoti, Afekhide and Pandit, Lekha and Paul, Friedemann and Rebolleda, Gema and Reddel, Stephen and Rejdak, Konrad and Rejdak, Robert and RodriguezandMorales, Alfonso J and Rougier, MarieandBenedicte and Sa, Maria Jose and SanchezandDalmau, Bernardo and Saylor, Deanna and Shatriah, Ismail and Siva, Aksel and StiebelandKalish, Hadas and Szatmary, Gabriella and Ta, Linh and Tenembaum, Silvia and Tran, Huy and Trufanov, Yevgen and Vincent, van Pesch and Wang, AnandGuor and Wattjes, Mike P and Willoughby, Ernest and Zakaria, Magd and Zvornicanin, Jasmin and Balcer, Laura and Plant, Gordon T}, article_location = {London, UK}, article_number = {12}, doi = {http://dx.doi.org/10.1016/S1474-4422(22)00200-9}, keywords = {optic neuritis; diagnosis; classification}, language = {eng}, issn = {1474-4422}, journal = {Lancet Neurology}, title = {Diagnosis and classification of optic neuritis}, url = {https://www.sciencedirect.com/science/article/pii/S1474442222002009?via%3Dihub}, volume = {21}, year = {2022} }
TY - JOUR ID - 2247589 AU - Petzold, Axel - Fraser, Clare L - Abegg, Mathias - Alroughani, Raed - Alshowaeir, Daniah - Alvarenga, Regina - Andris, Cecile - Asgari, Nasrin - Barnett, Yael - Battistella, Roberto - Behbehani, Raed - Berger, Thomas - Bikbov, Mukharram M - Biotti, Damien - Biousse, Valerie - Boschi, Antonella - Brázdil, Milan - Brezhnev, Andrei - Calabresi, Peter A - Cordonnier, Monique - Costello, Fiona - Cruz, Franz M - Cunha, Leonardo Provetti - Daoudi, Smail - Deschamps, Romain - Jerome, de Seze - Diem, Ricarda - Etemadifar, Masoud - Flores-Rivera, Jose - Fonseca, Pedro - Frederiksen, Jette - Frohman, Elliot - Frohman, Teresa - Tilikete, Caroline Froment - Fujihara, Kazuo - Galvez, Alberto - Gouider, Riadh - Gracia, Fernando - Grigoriadis, Nikolaos - Guajardo, Jose M - Habek, Mario - Hawlina, Marko - Martinez-Lapiscina, Elena H - Hooker, Juzar - Hor, Jyh Yung - Howlett, William - Huang-Link, Yumin - Idrissova, Zhannat - Illes, Zsolt - Jancic, Jasna - Jindahra, Panitha - Karussis, Dimitrios - Kerty, Emilia - Kim, Ho Jin - Lagreze, Wolf - Leocani, Letizia - Levin, Netta - Liskova, Petra - Liu, Yaou - Maiga, Youssoufa - Marignier, Romain - McGuigan, Chris - Meira, Dalia - Merle, Harold - Monteiro, Mario L R - Moodley, Anand - Moura, Frederico - Munoz, Silvia - Mustafa, Sharik - Nakashima, Ichiro - Noval, Susana - Oehninger, Carlos - Ogun, Olufunmilola - Omoti, Afekhide - Pandit, Lekha - Paul, Friedemann - Rebolleda, Gema - Reddel, Stephen - Rejdak, Konrad - Rejdak, Robert - Rodriguez-Morales, Alfonso J - Rougier, Marie-Benedicte - Sa, Maria Jose - Sanchez-Dalmau, Bernardo - Saylor, Deanna - Shatriah, Ismail - Siva, Aksel - Stiebel-Kalish, Hadas - Szatmary, Gabriella - Ta, Linh - Tenembaum, Silvia - Tran, Huy - Trufanov, Yevgen - Vincent, van Pesch - Wang, An-Guor - Wattjes, Mike P - Willoughby, Ernest - Zakaria, Magd - Zvornicanin, Jasmin - Balcer, Laura - Plant, Gordon T PY - 2022 TI - Diagnosis and classification of optic neuritis JF - Lancet Neurology VL - 21 IS - 12 SP - 1120-1134 EP - 1120-1134 PB - Elsevier SN - 14744422 KW - optic neuritis KW - diagnosis KW - classification UR - https://www.sciencedirect.com/science/article/pii/S1474442222002009?via%3Dihub N2 - There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can facilitate the timely treatment of individuals with multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein antibody-associated disease. Epidemiological data show that, cumulatively, optic neuritis is most frequently caused by many conditions other than multiple sclerosis. Worldwide, the cause and management of optic neuritis varies with geographical location, treatment availability, and ethnic background. We have developed diagnostic criteria for optic neuritis and a classification of optic neuritis subgroups. Our diagnostic criteria are based on clinical features that permit a diagnosis of possible optic neuritis; further paraclinical tests, utilising brain, orbital, and retinal imaging, together with antibody and other protein biomarker data, can lead to a diagnosis of definite optic neuritis. Paraclinical tests can also be applied retrospectively on stored samples and historical brain or retinal scans, which will be useful for future validation studies. Our criteria have the potential to reduce the risk of misdiagnosis, provide information on optic neuritis disease course that can guide future treatment trial design, and enable physicians to judge the likelihood of a need for long-term pharmacological management, which might differ according to optic neuritis subgroups. ER -
PETZOLD, Axel, Clare L FRASER, Mathias ABEGG, Raed ALROUGHANI, Daniah ALSHOWAEIR, Regina ALVARENGA, Cecile ANDRIS, Nasrin ASGARI, Yael BARNETT, Roberto BATTISTELLA, Raed BEHBEHANI, Thomas BERGER, Mukharram M BIKBOV, Damien BIOTTI, Valerie BIOUSSE, Antonella BOSCHI, Milan BRÁZDIL, Andrei BREZHNEV, Peter A CALABRESI, Monique CORDONNIER, Fiona COSTELLO, Franz M CRUZ, Leonardo Provetti CUNHA, Smail DAOUDI, Romain DESCHAMPS, de Seze JEROME, Ricarda DIEM, Masoud ETEMADIFAR, Jose FLORES-RIVERA, Pedro FONSECA, Jette FREDERIKSEN, Elliot FROHMAN, Teresa FROHMAN, Caroline Froment TILIKETE, Kazuo FUJIHARA, Alberto GALVEZ, Riadh GOUIDER, Fernando GRACIA, Nikolaos GRIGORIADIS, Jose M GUAJARDO, Mario HABEK, Marko HAWLINA, Elena H MARTINEZ-LAPISCINA, Juzar HOOKER, Jyh Yung HOR, William HOWLETT, Yumin HUANG-LINK, Zhannat IDRISSOVA, Zsolt ILLES, Jasna JANCIC, Panitha JINDAHRA, Dimitrios KARUSSIS, Emilia KERTY, Ho Jin KIM, Wolf LAGREZE, Letizia LEOCANI, Netta LEVIN, Petra LISKOVA, Yaou LIU, Youssoufa MAIGA, Romain MARIGNIER, Chris MCGUIGAN, Dalia MEIRA, Harold MERLE, Mario L R MONTEIRO, Anand MOODLEY, Frederico MOURA, Silvia MUNOZ, Sharik MUSTAFA, Ichiro NAKASHIMA, Susana NOVAL, Carlos OEHNINGER, Olufunmilola OGUN, Afekhide OMOTI, Lekha PANDIT, Friedemann PAUL, Gema REBOLLEDA, Stephen REDDEL, Konrad REJDAK, Robert REJDAK, Alfonso J RODRIGUEZ-MORALES, Marie-Benedicte ROUGIER, Maria Jose SA, Bernardo SANCHEZ-DALMAU, Deanna SAYLOR, Ismail SHATRIAH, Aksel SIVA, Hadas STIEBEL-KALISH, Gabriella SZATMARY, Linh TA, Silvia TENEMBAUM, Huy TRAN, Yevgen TRUFANOV, van Pesch VINCENT, An-Guor WANG, Mike P WATTJES, Ernest WILLOUGHBY, Magd ZAKARIA, Jasmin ZVORNICANIN, Laura BALCER and Gordon T PLANT. Diagnosis and classification of optic neuritis. \textit{Lancet Neurology}. London, UK: Elsevier, 2022, vol.~21, No~12, p.~1120-1134. ISSN~1474-4422. Available from: https://dx.doi.org/10.1016/S1474-4422(22)00200-9.