GENZOR, Samuel, Jan PRASKO, Jan MIZERA, Petr JAKUBEC, Milan SOVA, Jakub VANEK, Nikoleta SURINOVA and Katerina LANGOVA. Risk of Severe COVID-19 in Non-Adherent OSA Patients. PATIENT PREFERENCE AND ADHERENCE. AUCKLAND: DOVE MEDICAL PRESS LTD, 2022, vol. 16, November 2022, p. 3069-3079. ISSN 1177-889X. Available from: https://dx.doi.org/10.2147/PPA.S387657.
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Basic information
Original name Risk of Severe COVID-19 in Non-Adherent OSA Patients
Authors GENZOR, Samuel (203 Czech Republic), Jan PRASKO (203 Czech Republic, guarantor), Jan MIZERA (203 Czech Republic), Petr JAKUBEC (203 Czech Republic), Milan SOVA (203 Czech Republic, belonging to the institution), Jakub VANEK (203 Czech Republic), Nikoleta SURINOVA (203 Czech Republic) and Katerina LANGOVA (203 Czech Republic).
Edition PATIENT PREFERENCE AND ADHERENCE, AUCKLAND, DOVE MEDICAL PRESS LTD, 2022, 1177-889X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30203 Respiratory systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.200
RIV identification code RIV/00216224:14110/22:00128092
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.2147/PPA.S387657
UT WoS 000884754000001
Keywords in English OSA; COVID-19; vaccination; treatment with CPAP; CPAP adherence
Tags 14110215, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 18/1/2023 12:58.
Abstract
Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively. Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.
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