Risk of Severe COVID-19 in Non-Adherent OSA Patients

J 2022

Risk of Severe COVID-19 in Non-Adherent OSA Patients

GENZOR, Samuel, Jan PRASKO, Jan MIZERA, Petr JAKUBEC, Milan SOVA et. al.

Basic information

Original name

Risk of Severe COVID-19 in Non-Adherent OSA Patients

Authors

GENZOR, Samuel (203 Czech Republic), Jan PRASKO (203 Czech Republic, guarantor), Jan MIZERA (203 Czech Republic), Petr JAKUBEC (203 Czech Republic), Milan SOVA (203 Czech Republic, belonging to the institution), Jakub VANEK (203 Czech Republic), Nikoleta SURINOVA (203 Czech Republic) and Katerina LANGOVA (203 Czech Republic)

Edition

PATIENT PREFERENCE AND ADHERENCE, AUCKLAND, DOVE MEDICAL PRESS LTD, 2022, 1177-889X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30203 Respiratory systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.200

RIV identification code

RIV/00216224:14110/22:00128092

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.2147/PPA.S387657

UT WoS

000884754000001

Keywords in English

OSA; COVID-19; vaccination; treatment with CPAP; CPAP adherence

Abstract

V originále

Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively. Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.

Citovat

GENZOR, Samuel, Jan PRASKO, Jan MIZERA, Petr JAKUBEC, Milan SOVA, Jakub VANEK, Nikoleta SURINOVA and Katerina LANGOVA. Risk of Severe COVID-19 in Non-Adherent OSA Patients. PATIENT PREFERENCE AND ADHERENCE. AUCKLAND: DOVE MEDICAL PRESS LTD, 2022, vol. 16, November 2022, p. 3069-3079. ISSN 1177-889X. Available from: https://dx.doi.org/10.2147/PPA.S387657.

@article{2247601,
   author = {Genzor, Samuel and Prasko, Jan and Mizera, Jan and Jakubec, Petr and Sova, Milan and Vanek, Jakub and Surinova, Nikoleta and Langova, Katerina},
   article_location = {AUCKLAND},
   article_number = {November 2022},
   doi = {http://dx.doi.org/10.2147/PPA.S387657},
   keywords = {OSA; COVID-19; vaccination; treatment with CPAP; CPAP adherence},
   language = {eng},
   issn = {1177-889X},
   journal = {PATIENT PREFERENCE AND ADHERENCE},
   title = {Risk of Severe COVID-19 in Non-Adherent OSA Patients},
   url = {https://www.dovepress.com/risk-of-severe-covid-19-in-non-adherent-osa-patients-peer-reviewed-fulltext-article-PPA},
   volume = {16},
   year = {2022}
}

TY  - JOUR
ID  - 2247601
AU  - Genzor, Samuel - Prasko, Jan - Mizera, Jan - Jakubec, Petr - Sova, Milan - Vanek, Jakub - Surinova, Nikoleta - Langova, Katerina
PY  - 2022
TI  - Risk of Severe COVID-19 in Non-Adherent OSA Patients
JF  - PATIENT PREFERENCE AND ADHERENCE
VL  - 16
IS  - November 2022
SP  - 3069-3079
EP  - 3069-3079
PB  - DOVE MEDICAL PRESS LTD
SN  - 1177889X
KW  - OSA
KW  - COVID-19
KW  - vaccination
KW  - treatment with CPAP
KW  - CPAP adherence
UR  - https://www.dovepress.com/risk-of-severe-covid-19-in-non-adherent-osa-patients-peer-reviewed-fulltext-article-PPA
N2  - Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively. Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.
ER  -

GENZOR, Samuel, Jan PRASKO, Jan MIZERA, Petr JAKUBEC, Milan SOVA, Jakub VANEK, Nikoleta SURINOVA and Katerina LANGOVA. Risk of Severe COVID-19 in Non-Adherent OSA Patients. \textit{PATIENT PREFERENCE AND ADHERENCE}. AUCKLAND: DOVE MEDICAL PRESS LTD, 2022, vol.~16, November 2022, p.~3069-3079. ISSN~1177-889X. Available from: https://dx.doi.org/10.2147/PPA.S387657.

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