ADAM, Zdeněk, David ZEMAN, Aleš ČERMÁK, Milan DASTYCH, Martina DOUBKOVÁ, Teodor HORVÁTH, Šárka SKORKOVSKÁ, Zuzana ADAMOVÁ, Zdeněk ŘEHÁK, Renata KOUKALOVÁ, Luděk POUR, Martin ŠTORK, Marta KREJČÍ, Viera SANDECKÁ, Sabina ŠEVČÍKOVÁ and Zdeněk KRÁL. Onemocnění asociované s imunoglobulinem IgG4. Klinické příznaky, diferenciální diagnostika a recentní mezinárodní diagnostická kritéria (IgG4-related disease. Clinical manifestation differential diagnosis and recent International Diagnostic Criteria for IgG4-related disease). Vnitřní lékařství. Praha: Česká lékařská společnost J. E. Purkyně, 2022, vol. 68, No 5, p. "E4"-"E19", 16 pp. ISSN 0042-773X. Available from: https://dx.doi.org/10.36290/vnl.2022.070.
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Basic information
Original name Onemocnění asociované s imunoglobulinem IgG4. Klinické příznaky, diferenciální diagnostika a recentní mezinárodní diagnostická kritéria
Name (in English) IgG4-related disease. Clinical manifestation differential diagnosis and recent International Diagnostic Criteria for IgG4-related disease
Authors ADAM, Zdeněk (203 Czech Republic, guarantor, belonging to the institution), David ZEMAN (203 Czech Republic), Aleš ČERMÁK (203 Czech Republic, belonging to the institution), Milan DASTYCH (203 Czech Republic, belonging to the institution), Martina DOUBKOVÁ (203 Czech Republic, belonging to the institution), Teodor HORVÁTH (203 Czech Republic, belonging to the institution), Šárka SKORKOVSKÁ (203 Czech Republic, belonging to the institution), Zuzana ADAMOVÁ (203 Czech Republic), Zdeněk ŘEHÁK (203 Czech Republic), Renata KOUKALOVÁ (203 Czech Republic), Luděk POUR (203 Czech Republic, belonging to the institution), Martin ŠTORK (203 Czech Republic, belonging to the institution), Marta KREJČÍ (203 Czech Republic, belonging to the institution), Viera SANDECKÁ (703 Slovakia, belonging to the institution), Sabina ŠEVČÍKOVÁ (203 Czech Republic, belonging to the institution) and Zdeněk KRÁL (203 Czech Republic, belonging to the institution).
Edition Vnitřní lékařství, Praha, Česká lékařská společnost J. E. Purkyně, 2022, 0042-773X.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30203 Respiratory systems
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/22:00128166
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.36290/vnl.2022.070
Keywords (in Czech) IgG4 immunoglobulin subclass; IgG4 related disease
Keywords in English IgG4 immunoglobulin subclass; IgG4 related disease
Tags rivok
Tags Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 8/2/2023 14:41.
Abstract
Immunoglobulin G4-related disease (IgG4-RD) is a rare systemic fibro-inflammatory disorder. Autoimmune pancreatitis is the most frequent manifestation of IgG4-RD. However, IgG4-RD can affect any organ such as salivary glands, orbits, retroperito-neum, prostate and many others. Recent research enabled a clear clinical and histopathological description of IgG4-RD and in 2019 four Clinical phenotypes of IgG4-related disease were described. Diagnosis is based on morphological examination with typical findings of lymphoplasmocellular inflammation, storiform fibrosis and obliterative phlebitis in IgG4-RD biopsies and the tissue invading plasma cells largely produce IgG4. Elevated serum IgG4 levels are found in many but not all patients. New diagnostic criteria for IgG4-RD have been published recently in 2019 and 2021. This review summarizes current knowledge on pathophysiology, clinical manifestations, diagnosis and differential diagnosis of IgG4-RD from the point of view 2022 and in next article brings overview of the IgG4-RD therapy. © 2022, SOLEN s.r.o.. All rights reserved.
Abstract (in English)
Immunoglobulin G4-related disease (IgG4-RD) is a rare systemic fibro-inflammatory disorder. Autoimmune pancreatitis is the most frequent manifestation of IgG4-RD. However, IgG4-RD can affect any organ such as salivary glands, orbits, retroperito-neum, prostate and many others. Recent research enabled a clear clinical and histopathological description of IgG4-RD and in 2019 four Clinical phenotypes of IgG4-related disease were described. Diagnosis is based on morphological examination with typical findings of lymphoplasmocellular inflammation, storiform fibrosis and obliterative phlebitis in IgG4-RD biopsies and the tissue invading plasma cells largely produce IgG4. Elevated serum IgG4 levels are found in many but not all patients. New diagnostic criteria for IgG4-RD have been published recently in 2019 and 2021. This review summarizes current knowledge on pathophysiology, clinical manifestations, diagnosis and differential diagnosis of IgG4-RD from the point of view 2022 and in next article brings overview of the IgG4-RD therapy. © 2022, SOLEN s.r.o.. All rights reserved.
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